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UnknownIGF-1R down regulates the sensitivity of hepatocellular carcinoma to sorafenib through the PI3K / akt and RAS / raf / ERK signaling pathways.
Not available
S-EPMC9875405 | biostudies-literature
MetabolomicsTheabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
UnknownPreparation process of mesophase pitch-based carbon fiber: a review.
Not available
S-EPMC12536871 | biostudies-literature
GenomicsGlobal analysis of in vivo EGR1-binding sites in erythroleukemia cell K562 using chromatin immunoprecipitation and massively parallel sequencing
Early growth response gene 1 (EGR1) has been implicated in megakaryocyte differentiation induced by PMA (phorbol 12-myristate 13-acetate). The identification of direct EGR1 target genes in global scale is critical for our understanding of how EGR1 contributes to this process. In this study, we provi...
ORGANISM(S): Homo sapiens 
2010-09-08 | E-GEOD-21665 | biostudies-arrayexpress
UnknownMolecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Not available
S-EPMC10202051 | biostudies-literature
ProteomicsThe molecular mechanisms of imatinb treatment on acute lung injury in septic mice through proteomic technology
A septicemia model was established by intraperitoneal injection of lipopolysaccharide (LPS), followed by tail vein injection of imatinib in the treatment group and normal saline injection in the control group. Flow cytometry was used to detect inflammatory factors, and hematoxylin staining was used ...
ORGANISM(S): Mus Musculus 
2024-02-27 | PXD050204 |
ProteomicsIntegrated tissue proteome and metabolome reveal key elements and regulatory pathways in cutaneous squamous cell carcinoma
we took advantage of nanoscale liquid chromatography and quadrupole time-of-flight tandem mass spectrometry (nanoLC/Q-TOF-MS/MS) and ultraperformance LC/Q-TOF-MS/MS techniques on cancer and the corresponding paracancerous tissues from 20 CSCC patients for integrated proteomic and metabolomic analyse...
ORGANISM(S): Homo Sapiens 
2021-01-20 | PXD023716 |
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