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MetabolomicsUltraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model
This study aims to identify biomarkers for evaluating the therapeutic efficacy of mesalazine on ulcerative colitis by metabolomics and lipidomics. A dextran sulfate sodium-induced mouse model was used. The disease status was assessed by a disease activity index, the TNF-α level of colon was measured...
2022-10-24 | MTBLS2111 | MetaboLights
UnknownRegulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke.
Not available
S-EPMC3962686 | biostudies-literature
ProteomicsFibroblast-derived Smoothened governs prognosis of acute kidney injury
Although the tubule is the epicenter of damage, kidney fibroblast is increasingly appreciated in governing the prognosis of acute kidney injury (AKI). Smoothened (Smo), a heptahelical transmembrane protein, carries a hedgehog signal to mediate the communications between kidney fibroblasts and tubula...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-23 | MSV000088609 | MassIVE
UnknownGPR68 Is a Neuroprotective Proton Receptor in Brain Ischemia.
Not available
S-EPMC7678672 | biostudies-literature
TranscriptomicsMiR expression profiles in M1-polarized compared with unstimulated (MФ) bone marrow-derived macrophage cells
The global change of the miR expression profile during atherosclerosis is due to the infiltration of different types of leukocytes into the arterial vessel wall in addition to disease-specific regulation in vascular cells. Monocyte-derived macrophage accumulation in the subintimal region is critical...
ORGANISM(S): Mus musculus 
2012-12-26 | E-GEOD-33453 | biostudies-arrayexpress
UnknownDiscovery of the first selective and potent PROTAC degrader for the pseudokinase TRIB2.
Not available
S-EPMC12135709 | biostudies-literature
UnknownDevelopment of a Novel Quinoline Derivative as a P-Glycoprotein Inhibitor to Reverse Multidrug Resistance in Cancer Cells.
Not available
S-EPMC6955663 | biostudies-literature
ProteomicsPlasma proteomics dataset of COVID-19 patients
Quantitative proteomic analysis of plasma from different time courses of fatal, severe, and mild COVID-19 patients was performed to assess the biological changes during treatment.
ORGANISM(S): Homo Sapiens 
2020-06-22 | PXD019106 |
ProteomicsUrinary Proteomic Profiles of Anterior Cruciate Ligament Reconstruction Patients
A total of 30 ACLR patients, at least 9 months post-surgery, were recruited. Patients were divided into RTS and non-RTS groups based on their ability to return to sport, recovery to pre-injury Tegner levels, and a leg symmetry index of 85% on the single-leg hop test. Urine samples were analyzed usin...
ORGANISM(S): Homo Sapiens 
2025-02-19 | PXD060941 |
ProteomicsSTUB1 regulates antiviral RNAi through inducing ubiquitination and degradation of Dicer and AGO2 in mammals
Screening of the interacting molecular of AGO2 in mammals
ORGANISM(S): Homo Sapiens 
2022-03-28 | PXD032854 |
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