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3-Hydroxy-3-methylglutaryl-CoA synthase (HMGS) is the second enzyme in the mevalonate pathway. F-244 is the specific inhibitor of HMGS. F-244 treatment caused reduced primary root growth. SWATH-MS quantitative proteomics analysis was carried out to identify differential expressed proteins in F-244-t...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-10-01 | PXD009776 | Pride
Deep sequencing of mRNA from Fusarium oxysporum f. sp. Cubense 1 and 4 after infecting Musa acuminata 0h and 48h. Analysis of ploy(A)+ RNA of different hours after infecting of Musa acuminata
ORGANISM(S): Fusarium oxysporum f. cubense 
We incubated F. nucleatum lysates with biotinylated proteins from KRAS p.G12D, KRAS p.G13D and KRAS WT cells respectively. Subsequent western blot analysis showed that three candidate proteins from F. nucleatum might interact with KRAS p.G12D cells. The bands of interest were then submitted for mass...
ORGANISM(S): Fusobacterium nucleatum CTI-1 
2024-01-25 | PXD048686 | Pride
Many Gram-negative bacteria utilize the ubiquitous and versatile type VI secretion systems (T6SS) for diverse purposes, such as outcompeting other microbes or to successfully colonize hosts. T6SS of common pathogens are classified as T6SSi, but an outlier is the T6SSii and it is present only in the ...
ORGANISM(S): Francisella tularensis subsp. novicida (strain U112) 
2026-03-09 | PXD059583 | Pride
Alzheimer’s disease (AD) is the most common form of dementia in older adults and has a devastating impact on the patient’s quality of life, which creates a significant socio-economic burden for the affected individuals and their families. In recent years, studies have identified a relationship betwe...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD033147 | Pride
Here, in a time-course phosphoproteome analysis on Arabidopsis seedlings exposed to control or high ambient temperature, we observed reduced levels of diverse proteins over time, which could be in part due to transcription, translation and/or degradation. In addition, we observed differential phosph...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-05-26 | PXD035922 | Pride
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