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UnknownGANT61 suppresses proliferation and induces apoptosis in ALK-Positive anaplastic large cell lymphoma via modulating the Hh-PIK3IP1-Akt signaling axis.
Not available
S-EPMC12827395 | biostudies-literature
MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
UnknownElectroacupuncture potentiates peripheral CB2 receptor-inhibited chronic pain in a mouse model of knee osteoarthritis.
Not available
S-EPMC6231462 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
ProteomicsOne Brucella proteins solution sample, complete protein and 5 modifications Label-free omics research (No duplication,F8097WB remaining protein) analysis report.
Considering the role of PTMs(2-hydroxyisobutyrylation, succinylation, crotonylation, acetylation, and malonylation) in various biological processes of Brucella virulence and survival, we propose that the virulence of Brucella is associated with the PTMs of proteins. Taken together, this study provid...
ORGANISM(S): Brucella abortus (strain 2308) 
2022-03-04 | PXD030621 | Pride
Brucella 2308 lc-msms 
UnknownPyrotinib and chrysin synergistically potentiate autophagy in HER2-positive breast cancer.
Not available
S-EPMC10728098 | biostudies-literature
UnknownExploratory phase II trial of an anti-PD-1 antibody camrelizumab combined with a VEGFR-2 inhibitor apatinib and chemotherapy as a neoadjuvant therapy for triple-negative breast cancer (NeoPanDa03): efficacy, safety and biomarker analysis.
Not available
S-EPMC12279984 | biostudies-literature
ProteomicsPPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
Our study have shown that PPDPF promoted NF-κB activation through TRIM21-mediated K63-linked ubiquitination of RIPK1 in hepatocytes. Upon TNF-α stimulation, PPDPF enhances TRIM21/RIPK1 interaction and increases TRIM21-mediated K63-linked ubiquitination of RIPK1, which promotes NF-κB activation.To ma...
ORGANISM(S): Homo Sapiens 
2023-02-21 | PXD040301 |
ProteomicsGel-based LC-MSMS, the interactome of XAF1 in 293T cells
We utilized mass spectrometry to analyze the interacting proteins of XAF1 in 293T cells.
ORGANISM(S): Homo Sapiens 
2023-03-22 | PXD041021 |
TranscriptomicsMicroRNA-674-5p/5-LO axis is important in concanavalin A-induced acute mouse liver injury
Eight-week-old male pathogen-free BALB/c mice were used for the induction of concanavalin A (Con A)-induced hepatitis. Animals were acclimated for at least 6-7 days to a 12-hour light/dark cycle in a humidity- and temperature-controlled, specific-pathogen-free environment in autoclaved cages. Mice w...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-76345 | biostudies-arrayexpress
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