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ProteomicsN-acetyltransferase NAT10 Controls Cell Fates
Here, we show that NAT10 is an essential regulator of cellular plasticity, and its catalyzed mRNA cytidine acetylation represents a new layer of epitranscriptomic modulation.
ORGANISM(S): Homo sapiens (Human) 
2023-11-14 | PXD036888 | Pride
Cell-fate transition Nat10 Epitranscriptome 
UnknownSmall molecules promote CRISPR-Cpf1-mediated genome editing in human pluripotent stem cells.
Not available
S-EPMC5880812 | biostudies-literature
TranscriptomicsThe global gene expression pattern between human fibroblasts and human neural stem cells
Recent advances in direct reprogramming using cell type-specific transcription factors provide an unprecedented opportunity for rapid generation of desired human cell types from easily accessible tissues. However, due to the diversity of conversion factors that facilitate the process, an arduous scr...
ORGANISM(S): Homo sapiens 
2013-01-16 | E-GEOD-38045 | biostudies-arrayexpress
TranscriptomicsGene expression data of hepatocytes derived from human fibroblasts, human iPSCs, and human adult hepatocytes
Generation of human fibroblast-derived hepatocytes capable of extensive proliferation, as evidenced by significant liver repopulation of mice. Unlike current protocols for deriving hepatocytes from human fibroblasts, ours did not generate iPSCs, but shortcut reprogramming to pluripotency to generate...
ORGANISM(S): Homo sapiens 
2014-01-22 | E-GEOD-52309 | biostudies-arrayexpress
TranscriptomicsConversion of Epiblast Stem Cells to Embryonic Stem Cells by Small Molecules
Recently, (in vitro) pluripotent EpiSCs were derived from the post-implantation egg cylinder stage epiblasts of mouse and rat. These EpiSCs resemble and correspond very closely to the conventional human embryonic stem cells (hESCs) in the colony morphology and culture/signaling requirements for main...
ORGANISM(S): Mus musculus 
2010-10-30 | E-GEOD-17664 | biostudies-arrayexpress
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