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ProteomicsStabilization of Pin1 by USP34 promotes Ubc9 isomerization and protein sumoylation in glioma stem cells to augment glioblastoma malignancy
he unique prolyl isomerase Pin1 that promotes protein conformational changes is a pivotal therapeutic target in many cancers, but little is known about the regulation of Pin1 protein stability. We previously found that Pin1 was highly expressed in glioma stem cells (GSCs) relative to non-stem tumor ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD041043 | Pride
Deubiquitination Ls-ms/ms Pin1 
MetabolomicsMetabolome-based prediction of yield heterosis contributes to the breeding of elite rice
The improvement of breeding efficiencies for heterotic and climate-resilient crops can mitigate the food shortage crisis from overpopulation and climate change. Thus far, diverse molecular markers have been utilized for guiding field phenotypic selections, while the accurate predictions of complex h...
2019-12-10 | MTBLS742 | MetaboLights
MetabolomicsA high-resolution Orbitrap mass spectral library for trace volatile compounds in fruit wines
The overall aroma is an important factor of the sensory quality of fruit wines, which attributed to hundreds of volatile compounds. However, the qualitative determination of trace volatile compounds is considered to be very challenging work. GC-Orbitrap-MS with high resolution and high sensitivity p...
2022-08-12 | MTBLS3840 | MetaboLights
ProteomicsMass spectrometry for proteomic analysis
ARF1-Flag and its palmitoylation-deficient mutant (C159A-Flag) were purified by immunoprecipitation separately. The purified proteins were digested and analyzed by LC-MS-based quantitative proteomics to identify differential interactors and binding affinity changes induced by ARF1 palmitoylation. Th...
ORGANISM(S): Mus Musculus 
2026-04-27 | PXD072413 |
UnknownContinuous positive airway pressure (CPAP) vs noninvasive positive pressure ventilation (NIPPV) vs noninvasive high frequency oscillation ventilation (NHFOV) as post-extubation support in preterm neonates: protocol for an assessor-blinded, multicenter, randomized controlled trial.
Not available
S-EPMC6659219 | biostudies-literature
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