Sort   by:  
 Page size 
ProteomicsO-GlcNAcylation promotes Palbociclib resistance in breast cancer by regulating MITF nuclear translocation
Cyclin-dependent kinases 4 and 6 (CDK4/6) are essential drivers of the cell cycle and are also critical for the initiation and progression of diverse malignancies. Pharmacological inhibitors targeting CDK4/6 have demonstrated significant activity against various tumor types such as breast cancer. Ho...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD042763 | Pride
O-glcnacylation Mitf Palbociclib 
ProteomicsO-GlcNAcylation promotes Palbociclib resistance in breast cancer by regulating MITF nuclear translocation
Cyclin-dependent kinases 4 and 6 (CDK4/6) are essential drivers of the cell cycle and are also critical for the initiation and progression of diverse malignancies. Pharmacological inhibitors targeting CDK4/6 have demonstrated significant activity against various tumor types such as breast cancer. Ho...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD042838 | Pride
Mitf Palbociclib O-glcnac 
ProteomicsHuman HEK293T cells LC-MS/MS (Gel-based proteomics)
Fanconi Anemia (FA) pathway is essential for the repair of inter-strand crosslink (ICLs). ICL induces stalled replication forks and triggers activation of FA pathway for efficient ICL repair. Given that stalled replication fork is proximal to ICLs sites, fork-associated proteins may likely coordinat...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD028246 | Pride
Fanconi anemia pathway Human cells Wdhd1 
ProteomicsAnd-1 is required for NER repair and promotes skin carcinogenesis
Our project was focused on And-1 regulates NER repair and skin carcinogenesis
ORGANISM(S): Homo sapiens (Human) 
2025-08-21 | PXD052800 | Pride
And-1 Ner repair Skin carcinogenesis 
Sort   by:  
 Page size