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ProteomicsCoupled protein synthesis and ribosome-guided piRNA processing on mRNAs
PIWI-interacting small RNAs (piRNAs) protect the germline genome and are essential for fertility. Previously, we showed that ribosomes guide the biogenesis of piRNAs from long non-coding RNAs (lncRNAs) after translating the short open reading frames (ORFs) near their 5′ cap. It remained unclear, how...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-17 | PXD027489 | Pride
Mouse Protein synthesis Pirna Mrna Testis Lc-ms/ms 
ProteomicsA Novel Classifier Based on Urinary Proteomics for Distinguishing between Benign and Malignant Ovarian Tumors
Preoperative differentiation of benign and malignant tumor types is critical for providing individualized treatment interventions to improve prognosis of patients with ovarian cancer. High-throughput proteomics analysis of urine samples was performed to identify reliable and non-invasive biomarkers ...
ORGANISM(S): Homo Sapiens 
2021-08-04 | PXD027695 |
ProteomicsComparative Proteome Analysis of Four Sorghum Varieties Response to PEG Stress
Comparative Proteome Analysis of Four Sorghum Varieties Response to PEG Stress
ORGANISM(S): Sorghum Bicolor X Saccharum Hybrid Cultivar 
2022-05-12 | PXD033820 |
ProteomicsUbiquitome profiling reveals the landscape of ubiquitination regulation in young panicle
Ubiquitome profiling reveals the landscape of ubiquitination regulation in young panicle
ORGANISM(S): Oryza Sativa 
2017-12-11 | PXD023306 |
ProteomicsResistance prediction in HGSOC with NACT using data-independent acquisition proteomics and an ovarian tissue-specific spectral library
We firstly built a high-quality ovarian tissue-specific spectral library containing 130,735 peptides and 10,696 proteins on Orbitrap instruments. Compared to a published pan-human spectral library (DPHL), this spectral library provides 10% more ovary-specific and 3% more ovary-enriched proteins. Thi...
ORGANISM(S): Homo Sapiens 
2023-01-02 | PXD039160 |
ProteomicsDPHL v2: An updated and comprehensive DIA pan-human assay library for quantifying more than 14,000 proteins
we generated DPHL v2 from 1608 DDA-MS data acquired using Orbitrap mass spectrometers. The data included 586 DDA-MS newly acquired from 17 tissue types, while 1022 files were derived from DPHL v1. DPHL v2 thus comprises data from 24 sample types, including several cancer types . We generated four va...
ORGANISM(S): Homo Sapiens 
2023-01-18 | PXD039313 |
ProteomicsComputational Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage and Applications to 15 Tumors
a computational strategy for the size optimization of DIA spectral library, which refines a comprehensive library by a prior analysis of DIA data of a particular tissue type
ORGANISM(S): Homo Sapiens 
2021-12-27 | PXD030648 |
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