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ProteomicsProteomic and functional analyses of the periodic membrane skeleton in neurons
Actin, spectrin, and associated proteins form a membrane-associated periodic skeleton (MPS) in neurons. The molecular composition and functions of the MPS remain incompletely understood. Here, we combined co-immunoprecipitation and mass spectrometry analyses to identify candidate MPS-interacting pro...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-04 | PXD030886 | Pride
Neuron Proteomics Actin Membrane skeleton Spectrin 
MetabolomicsEnergy-stress-mediated AMPK activation inhibits ferroptosis

Energy stress depletes ATP and induces cell death. Here we identify an unexpected inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation. We found that ferroptotic cell death and lipid peroxidation can be inhibited by treatment...

2023-01-31 | MTBLS1399 | MetaboLights
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S-EPMC11505515 | biostudies-literature
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