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ProteomicsProteomic characterization of hepatic expression signatures affected in ZHX2 liver conditional knockout mice
The liver has an exceptional capacity for regeneration which is crucial for maintaining liver function. Since transcriptional regulation of genes controlling metabolism and cell division is a hallmark of liver regeneration (LR), we investigated the role of Zinc-finger and homeboxes 2 (ZHX2), a trans...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-17 | PXD027897 | Pride
Mouse Zhx2 Proteome sequencing Liver 
GenomicsRole of ZHX2 in VSMCs [Chip-seq]
Role of ZHX2 in VSMCs [Chip-seq]
PRJNA1023579 | ENA
GenomicsRole of ZHX2 in VSMCs [RNA-seq]
Role of ZHX2 in VSMCs [RNA-seq]
PRJNA1023580 | ENA
GenomicsUSP13 Promotes Deubiquitination of ZHX2 and Tumorigenesis in Kidney Cancer
USP13 Promotes Deubiquitination of ZHX2 and Tumorigenesis in Kidney Cancer
PRJNA775640 | ENA
GenomicsZHX2 Promotes HIF1a Oncogenic Signaling in Triple-Negative Breast Cancer
ZHX2 Promotes HIF1a Oncogenic Signaling in Triple-Negative Breast Cancer
PRJNA732468 | ENA
ProteomicsValidation studies and multi-omics analysis of Zhx2 as a candidate quantitative trait gene underlying brain oxycodone metabolite (oxymorphone) levels and behavior
Sensitivity to the subjective reinforcing properties of opioids has a genetic component and can predict addiction liability of opioid compounds. We previously identified Zhx2 as a candidate gene underlying increased brain concentration of the oxycodone (OXY) metabolite oxymorphone (OMOR) in BALB/cJ ...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-30 | PXD056873 | Pride
Multiomics Mouse Brain 
UnknownZHX2 in health and disease.
Not available
S-EPMC9718504 | biostudies-literature
GenomicsRole of ZHX2 in VSMCs [Chip-seq]
In order to explore the biological function and molecular mechanism of ZHX2 in VSMCs,in this study, we overexpressed ZHX2 in primery VSMCs used chromatin immunoprecipitation sequencing (ChIP-seq) methods to systematically investigate the downstream targets of ZHX2.
ORGANISM(S): Rattus norvegicus 
2023-10-07 | GSE244563 | GEO
GenomicsGene expression profiling of 786-O cells with ZHX2 and p65 knockdown
Gene expression profiling of 786-O cells with ZHX2 and p65 knockdown
PRJNA432739 | ENA
TranscriptomicsRole of ZHX2 in VSMCs [RNA-seq]
Primary rat VSMCs were infected with Ad-Control and Ad-ZHX2 and stimulated with PDGF-BB of 24h. RNAseq and differential expression analysis were performed to investigate the role of ZHX2 in VSMCs.
ORGANISM(S): Rattus norvegicus 
2023-10-07 | GSE244564 | GEO
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