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TranscriptomicsTranscriptional profiling of iPSC derived motor neurons from spinal and bulbar muscular atrophy patients at key stages motor neurogenesis
Characterise the molecular pathogenesis of androgen receptor spinal and bulbar muscular atrop (SBMA) causing repeat expansion mutations in human motor neurons generated from patient-specific spinal cord motor neurons from induced pluripotent stem cells and performed time-resolved analysis of transcr...
ORGANISM(S): Homo sapiens 
2026-08-01 | E-MTAB-15765 | biostudies-arrayexpress
TranscriptomicsCD34 negative populations are associated with an increased relapse risk in childhood AML and harbor chemo-resistant leukemia stem cells
Differences in chemo-sensitivity of subpopulations of AML stem cells could have important clinical implications. Using in vitro cytotoxicity, xenograft models and colony forming assays, we compared chemotherapy sensitivity between Lineage (Lin-)CD34-CD38-, Lin-CD34-CD38+, Lin-CD34+CD38- and Lin-CD34...
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-45249 | biostudies-arrayexpress
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