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UnknownAdjuvant hypofractionated radiotherapy with simultaneous integrated boost after breast-conserving surgery: results of a prospective trial.
Not available
S-EPMC7801347 | biostudies-literature
TranscriptomicsExpression data from murine fibroblasts overexpressing Fbxl10
Posttranslational modifications on histone tails control gene expresssion levels in an either positive or negative way. Therefore enzymes which modifiy the modifications on the histon tails, like histone demethylases, are able to strictly regulate the transcriptom. To analyse the regulatory role of ...
ORGANISM(S): Mus musculus 
2012-10-05 | E-GEOD-34691 | biostudies-arrayexpress
TranscriptomicsTranscription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice
Maintenance and maturation of primordial germ cells is controlled by complex genetic and epigenetic cascades, and disturbances in this network lead to either infertility or malignant aberration. Transcription factor Tcfap2c / TFAP2C has been described to be essential for primordial germ cell mainten...
ORGANISM(S): Mus musculus 
2014-01-30 | E-GEOD-45941 | biostudies-arrayexpress
TranscriptomicsPurification of neuronal precursors from the adult mouse brain: a comprehensive gene expression analysis
The progeny of neural stem cells in the subventricular zone (SVZ) of the adult mammalian brain consists in polysialylated NCAM-expressing immature neurons (PSA(+) cells), which migrate to the olfactory bulb (OB) to differentiate into GABAergic interneurons. We purified murine PSA(+) cells directly f...
ORGANISM(S): Mus musculus 
2007-09-21 | E-GEOD-9081 | biostudies-arrayexpress
UnknownElectron-Beam-Initiated Crosslinking of Methacrylated Alginate and Diacrylated Poly(ethylene glycol) Hydrogels.
Not available
S-EPMC10747465 | biostudies-literature
TranscriptomicsCrosstalk between very different family members: How STAT3 activating IL6-type cytokines inhibit the IFNg-like responses of IL27 in hepatocellular carcinoma cells
Interleukin-27 (IL27) is a type-I-cytokine of the IL6/IL12 family predominantly secreted by activated macrophages and dendritic cells. Best understood are the effects of IL27 on immune cells where it has been described to have pro- or anti-inflammatory properties, either promoting TH1 responses or s...
ORGANISM(S): Homo sapiens 
2017-07-05 | E-MTAB-4570 | biostudies-arrayexpress
ProteomicsFishing for SAM/SAH-binding proteins
The aim of the project was to identify S-adenodsyl methionine-binding proteins expressed in D. melanogaster S2 cells. For this puprose a capture compund reagent carrying a SAH-affinity group, a biotin group for enrichment and a cross-linking moiety consisting of either benzophenone or a nitrobenzen...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2019-02-25 | PXD006245 | Pride
Capture compound S-adenosyl-methionine Lysine methylation Methyltransferase 
ProteomicsStability of peptide fragmentation patterns
Our study aims to determine the stability of fragmetnation patterns of peptides upon collision-induced dissociation (CID). Recent studies reported that for a minority of peptides, CID fragmentation leads to non-reproducible fragmentation spectra and therefore impaired identification. In order to stu...
ORGANISM(S): Homo sapiens (Human) 
2019-02-25 | PXD006691 | Pride
Peptide fragmentation Peptide identification Collision-induced dissociation Tandem ms 
ProteomicsProteome analysis of Jurkat cells for spectral library
In order to increase the spectral library to study the ocurrence of distinct peptide fragmetation patterns, we analyzed the whole cell proteome of Jurkat cells.
ORGANISM(S): Homo sapiens (Human) 
2019-02-25 | PXD005111 | Pride
Spectral library Fragmentation pattern Whole cell lysate 
ProteomicsIdentification of human membrane proteins
Typically, integral membrane and membrane associate proteins are underrepresented in proteomic experiments due to their low abundance and solubility during sample preparation. We collected two fractions upon cell lysis, one comprising the insoluble membrane fraction the other the soluble cytosolic f...
ORGANISM(S): Homo sapiens (Human) 
2019-02-25 | PXD005063 | Pride
Membrane proteins Quantitatie proteomics 
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