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TranscriptomicsCharacterization of enterotropic CD4 T cells reaching the tdLN after antibiotics
4 groups of mice : Control, antibiotics, antibiotics + 4days of recolonization, antibiotics + 4days of recolonization + Enterocloster clostridioformis. Tumor draining lymph node were harvested after CFSE injection were harvested and CFSE+ cells were sorted and proccessed in order to generate single ...
ORGANISM(S): Mus musculus 
2023-05-31 | E-MTAB-12784 | biostudies-arrayexpress
TranscriptomicsBulk transcription RNA sequencing of a4b7high versus a4b7- CD4+ T cells from mesenteric lymph node in MCA205 tumor bearing mice
a4b7high and a4b7- CD4 T cells from mLN were sorted from respectively 5 mice. 4 independent samples for a4b7- and 5 independent samples for a4b7high CD4 T cells.
ORGANISM(S): Mus musculus 
2023-06-01 | E-MTAB-12787 | biostudies-arrayexpress
TranscriptomicsscRNAseq of Mus musculus ileum samples with RET melanoma against non-xenograft mice controls
Compare cell type proportion and gene expression between 3 mice with RET and 3 mice control
ORGANISM(S): Mus musculus 
2021-12-26 | E-MTAB-11242 | biostudies-arrayexpress
TranscriptomicsClonal and functional patterns of emigrating Treg cells according to locations
Single-cell TCR and RNA sequencing of recovered T cells in mLN, cLN, tdLN and tumor bed 24 hours post inoculation of CFSE in mLN.
ORGANISM(S): Mus musculus 
2023-07-01 | E-MTAB-12846 | biostudies-arrayexpress
TranscriptomicsExpression data of IL-18 generated murine NK cells
We analyzed gene expression profiles of IL-18 generated murine NK cells in comparison to unstimulated, freshly isolated splenic NK cells. We identified a set of 1414 Affymetrix probe sets showing significant misregulation (Welch's T-test, p<0.05; Benjamini-Hochberg FDR corrected). IL-18 generated as...
ORGANISM(S): Mus musculus 
2012-07-10 | E-GEOD-33627 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cell lines treated with cytochalasin D and nocodazole with the aim of characterising tetraploid clones
During the oncogenic process, tetraploidy is a candidate intermediate stage leading from diploidy to aneuploidy. The aim of our experiment was to establish tetraploid clones and to characterize their transcriptome.
ORGANISM(S): Homo sapiens 
2006-03-01 | E-TABM-70 | biostudies-arrayexpress
TranscriptomicsImpact of fecal microbiota transplantation (FMT) in 3 days-ABX-treated recipient mice using feces from 6 NSCLC patients at diagnosis.
This study aimed to analyze changes in gut microbiota composition in mice after transplantation of fecal microbiota (FMT, N = 6) from the feces of NSCLC patients by analyzing fecal content using 16S rRNA sequencing, 10 days after transplantation. Specific-pathogen-free (SPF) mice were used for each ...
ORGANISM(S): Mus musculus 
2023-07-01 | E-MTAB-12812 | biostudies-arrayexpress
TranscriptomicsCCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors post-chemotherapy
Analysis of MCA205 tumors developed in C57bl/6 mice on day 2, 7 and 10 after intratumoral treatment with doxorubicin (DX) or PBS solvent. DX triggers the immunogenicity of dying tumor cell and activates anti-tumor immunity. Results provided insight into molecular basis of DX induced immune response....
ORGANISM(S): Mus musculus 
2014-02-04 | E-GEOD-46275 | biostudies-arrayexpress
TranscriptomicsEssential role of formyl peptide receptor 1 in anthracycline-based anticancer chemotherapy
Tumor growth reduction induced by anthracycline-based chemotherapy is largely determined by an anticancer immune response that is ignited by the presentation of dead-cell antigens by intratumoral dendritic cells. In an unbiased screen designed to identify cancer therapy-relevant single nucleotide po...
ORGANISM(S): Mus musculus 
2016-04-04 | E-GEOD-63410 | biostudies-arrayexpress
TranscriptomicsRNA-seq of RBC depleted whole blood from COVID-19 patients and controls
Red blood cells (RBC) depleted whole blood from COVID-19 patients and controls was harvested and processed in order to performed 10X single cell RNA-seq. For COVID-19 patients 2 samples 10 days a part were analyzed.
ORGANISM(S): Homo sapiens 
2020-08-21 | E-MTAB-9221 | biostudies-arrayexpress
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