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UnknownMisleading Germ Cell Phenotype in Pulmonary NUT Carcinoma Harboring the ZNF532-NUTM1 Fusion.
Not available
S-EPMC8741879 | biostudies-literature
ProteomicsOncogenic BRD4-NUT protein interactions
To investigate the mechanism that drives dramatic mistargeting of active chromatin in NUT midline carcinoma, we have identified protein interactions unique to the BRD4-NUT fusion oncoprotein compared to wild type BRD4. Using crosslinking, affinity purification, and mass spectrometry, we identified ...
ORGANISM(S): Homo sapiens (Human) 
2017-04-05 | PXD005786 | Pride
Biotap-xl Znf532-nut Hyperacetylation Topological domains 
TranscriptomicsChromatin-associated protein interactions drive megadomain formation in NUT midline carcinoma
To investigate the mechanism that drives dramatic mistargeting of active chromatin in NUT-midline carcinoma, we have identified protein interactions unique to the BRD4-NUT fusion oncoprotein compared to wild type BRD4. Using crosslinking, affinity purification, and mass spectrometry, we identify the...
ORGANISM(S): Homo sapiens 
2017-08-22 | GSE96775 | GEO
UnknownEctopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.
Not available
S-EPMC5448232 | biostudies-literature
Unknown"Z4" Complex Member Fusions in NUT Carcinoma: Implications for a Novel Oncogenic Mechanism.
Not available
S-EPMC6279489 | biostudies-literature
GenomicsHomo sapiens
Chromatin-associated protein interactions drive megadomain formation in NUT midline carcinoma
PRJNA379616 | ENA
TranscriptomicsOptical Genome Mapping Identifies a Novel Pediatric Embryonal Tumor Subtype with a ZNF532-NUTM1 Fusion [RNA-seq]
Molecular characteristics of pediatric brain tumors have not only allowed for tumor subgrouping but have introduced novel treatment options for patients with specific tumor alterations. Therefore, an accurate histologic and molecular diagnosis is critical for optimized management of all pediatric pa...
ORGANISM(S): Homo sapiens 
2023-02-28 | GSE225965 | GEO
Methylation profilingOptical Genome Mapping Identifies a Novel Pediatric Embryonal Tumor Subtype with a ZNF532-NUTM1 Fusion [methylation]
Molecular characteristics of pediatric brain tumors have not only allowed for tumor subgrouping but have introduced novel treatment options for patients with specific tumor alterations. Therefore, an accurate histologic and molecular diagnosis is critical for optimized management of all pediatric pa...
ORGANISM(S): Homo sapiens 
2023-02-28 | GSE226220 | GEO
GenomicsOptical Genome Mapping Identifies a Novel Pediatric Embryonal Tumor Subtype with a ZNF532-NUTM1 Fusion [methylation]
Optical Genome Mapping Identifies a Novel Pediatric Embryonal Tumor Subtype with a ZNF532-NUTM1 Fusion [methylation]
PRJNA939180 | ENA
GenomicsOptical Genome Mapping Identifies a Novel Pediatric Embryonal Tumor Subtype with a ZNF532-NUTM1 Fusion [RNA-seq]
Optical Genome Mapping Identifies a Novel Pediatric Embryonal Tumor Subtype with a ZNF532-NUTM1 Fusion [RNA-seq]
PRJNA938115 | ENA
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