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TranscriptomicsKnockdown of Zona Pellucida protein 2 (ZP2) in mouse embryos by Trim-away and morpholino combined
The zona pellucida (Zp) genes are quintessential oocyte-specific genes that are transcribed only during oogenesis and whose protein products are secreted in the extracellular space. In mice the Zp genes are three: Zp1, Zp2, Zp3 (Zp4 is a pseudogene). Contrary to longtime knowledge, data from 2023 ha...
ORGANISM(S): Mus musculus 
2025-12-19 | E-MTAB-16339 | biostudies-arrayexpress
UnknownZona pellucida glycoproteins.
Not available
S-EPMC2528931 | biostudies-literature
ProteomicsEgg-coat degradation
Vertebrate oocytes are coated with a special extracellular matrix termed egg-coat or Zona pellucida (ZP). Egg-coat is constituted by several ZP glycoproteins. In chicken fertilization, ejaculated sperm releases enzyme(s) to solubilize the ZP glycoprotein(s) for penetrating the egg-coat. In this stud...
ORGANISM(S): Gallus Gallus 
2019-08-01 | PXD013994 | JPOST Repository
GenomicsZona pellucida removal affects pre- and post-implantation development and gene expression in mouse embryos
Zona pellucida removal affects pre- and post-implantation development and gene expression in mouse embryos
PRJNA821160 | ENA
TranscriptomicsZona pellucida removal affects pre- and post-implantation development and gene expression in mouse embryos
The zona pellucida plays a crucial role in the process of fertilization to early embryonic development, including cellular arrangement and communication between blastomeres. However, little is known regarding the role of the zona pellucida in pre- and post-implantation embryonic development associat...
ORGANISM(S): Mus musculus 
2022-03-31 | GSE199670 | GEO
ProteomicsSpecificity of the protase acrosin in zona pellucida proteins
This study aims to characterize the sperm protease acrosin.
ORGANISM(S): Mus musculus (Mouse) Sus scrofa domesticus (domestic pig) 
2021-04-09 | PXD023659 | Pride
Mammalian fertilization Fetuin-b Zona pellucida Ovastacin Acrosin 
ProteomicsSubstrate profiling of the metalloproteinase ovastacin – Implications for its physiological function in mammalian fertilization
The metalloproteinase ovastacin is released by the mammalian oocyte upon fertilization and cleaves zona pellucida protein 2, a component of the surrounding extracellular matrix, at a distinct cleavage site. This limited proteolysis hardens the zona pellucida, abolishes sperm binding and thereby regu...
ORGANISM(S): Mus Musculus (mouse) 
2023-09-15 | PXD038561 | JPOST Repository
ProteomicsProteomic dataset of ZP proteins from young- and middle-aged mice
This dataset includes a proteomic analysis of the ZP protein isolated from MII oocytes in young- and middle-aged mice.
ORGANISM(S): Mus Musculus (mouse) 
2024-11-18 | PXD056890 | JPOST Repository
TranscriptomicsGlobal Deterministic and Stochastic Allelic Specific Gene Expression in Single Blastomeres of Mouse Early Embryos
Here we modified a single cell whole transcriptome amplification method to make it capable of amplifying cDNAs as long as 3kb efficiently and unbiasedly. We combined this modified single cell cDNA amplification method with Applied Biosystems next generation sequencing SOLiD™ System to set up a singl...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-22182 | biostudies-arrayexpress
UnknownAvailability of empty zona pellucida for generating embryonic chimeras.
Not available
S-EPMC4412630 | biostudies-literature
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