After transferring the Sub1 Flag plasmid into HL-1 cells, the cells were treated with bleomycin for 24 hours, followed by immunoprecipitation using Flag magnetic beads and protein mass spectrometry.
Background:Episodic memory loss is a prominent clinical manifestation of Alzheimer's disease(AD), which is closely related to tau pathology and hippocampal impairment. Given the heterogeneity of brain neurons, the precise role of different brain neurons in terms of their sensitivity to tau accumulat...
