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MetabolomicsFlavonoid Biosynthesis Is Likely More Susceptible to Elevation and Tree Age Than Other Branch Pathways Involved in Phenylpropanoid Biosynthesis in Ginkgo Leaves
Ginkgo leaves are always resources for flavonoids pharmaceutical industry. However, the effect of the elevation and tree age changes on flavonoid biosynthesis have not been detailly explored in Ginkgo leaves. In addition, whether these environmental pressures have similar effects on the biosynthesis...
2020-12-14 | MTBLS962 | MetaboLights
ProteomicsHs_Hela_Phospho_Gluc
Hs Hela Cell, Ti4+-IMAC phospho enrichment, Gluc digest
ORGANISM(S): Homo Sapiens (human) 
2012-12-31 | PAe005275 | PeptideAtlas
ProteomicsHs_Hela_Phospho_Trypsin
Hs Hela Cell, Ti4+-IMAC phospho enrichment, Trypsin digest
ORGANISM(S): Homo Sapiens (human) 
2012-12-31 | PAe005251 | PeptideAtlas
ProteomicsAged skin exacerbates experimental osteoarthritis via enhanced IL-36R signaling
Increasing evidence suggests that age-related inflammation plays a pivotal role in osteoarthritis (OA) pathogenesis, but the mechanism is not fully understood. Here, we demonstrate that skin aging is an important driver of experimental OA progression in male mice via enhanced IL-36 receptor (IL-36R)...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD062165 | Pride
Aged skin Il-36 receptor antagonist Osteoarthritis Microneedles Senescent keratinocytes 
MetabolomicsMitochondrial Transplantation Ameliorates Doxorubicin-Induced Cardiac Dysfunction via Activating Glutamine Metabolism
Doxorubicin is a wildly used effective anticancer agent. However, doxorubicin use is also related to cardiotoxic side effect in some patients. Mitochondrial damage has been shown to be one of the pathogeneses of doxorubicin-induced myocardial injury. In this study, we test the hypothesis that mitoch...
2025-03-13 | MTBLS7989 | MetaboLights
ProteomicsRNA Pull-Down identifies the interactive proteins with tRF-Gln-CTG-026 in HL-7702 and AML12 cells
RNA Pull-Down identifies the interactive proteins with tRF-Gln-CTG-026 in HL-7702 and AML12 cells
ORGANISM(S): Homo Sapiens Mus Musculus 
2022-04-08 | PXD033097 |
ProteomicsMiRNA-378a-5p attenuates the development of abdominal aortic aneurysm via ABLIM1-MKL1 signaling pathways
Abstract Objectives: Abdominal aortic aneurysm (AAA) is a fatal cardiovascular disease with no effective drug treatment currently available. The aberrant expressions of microRNAs (miRNAs) contribute to AAA pathogenesis. In this study, we aimed to perform miRNA microarray analysis to screen for diffe...
ORGANISM(S): Homo Sapiens 
2026-01-13 | PXD073033 |
ProteomicsPotential binding partners of NUDT13 in DLD-1
To explore the role of NUDT13 in the initiation and progression of CRC, we performed NUDT13 immunoprecipitation in DLD-1 following LC-MS/MS analysis.
ORGANISM(S): Homo Sapiens 
PXD041430 |
ProteomicsMS analysis of endogenously precipitated DDX20 protein complexes (immunoprecipitation (IP)–MS)
Protein lysates were derived from HEK293T cells and spermatogonial stem cells，and interacting proteins were “pulled-down” for analysis by gel electrophoresis and identification by mass spectrometry. An equal amount of non-specific IgG from rabbit serum (Thermos Fisher Scientific) was used as a negat...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD038171 |
ProteomicsProteomic analysis of the effects of DDX20 deletion in spermatogonia
To investigate the role of DDX20 in spermatogenesis, we generated Ddx20 flox/flox Ddx4-Cre mice to make a germ cell-specific Ddx20 knockout, and isolated spermatogonia from four-day-old mouse testes by THY1 magnetic beads. We then performed proteomic analysis using protein lysates obtained from THY1...
ORGANISM(S): Mus Musculus 
PXD038170 |
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