Sort   by:  
 Page size 
TranscriptomicsInducible PAX5 expression in a human B lymphoblastic leukemia cell line
Hypomorphic mutations of the transcription factor PAX5 occur in one third of B-progenitor acute lymphoblastic leukemias (B-ALLs). To identify PAX5-regulated genes in B-ALL, here we employ inducible expression of PAX5 in a human B-ALL cell line (REH) that harbors a loss-of-function mutation in PAX5. ...
ORGANISM(S): Homo sapiens 
2014-06-18 | E-GEOD-57480 | biostudies-arrayexpress
TranscriptomicsRNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukemia
Epigenetic pathways regulate gene expression by controlling and interpreting chromatin modifications. Cancer cells are characterized by altered epigenetic landscapes and commonly exploit the chromatin regulatory machinery to enforce oncogenic gene expression programs. While chromatin alterations are...
ORGANISM(S): Homo sapiens 
2011-08-03 | E-GEOD-29799 | biostudies-arrayexpress
TranscriptomicsStage-specific control of early B cell development by the transcription factor Ikaros
Ikaros is an essential regulator of lymphopoiesis. Here, we studied the B-cell-specific function of Ikaros by conditional Ikzf1 inactivation in pro-B cells. B-cell development was arrested at an aberrant ‘pro-B’ cell stage characterized by increased cell adhesion and loss of pre-B cell receptor sign...
ORGANISM(S): Mus musculus 
2014-02-09 | E-GEOD-53595 | biostudies-arrayexpress
UnknownPrevalence of RT-qPCR-detected SARS-CoV-2 infection at schools: First results from the Austrian School-SARS-CoV-2 prospective cohort study.
Not available
S-EPMC8350968 | biostudies-literature
UnknownIn-situ high-resolution cryo-EM reconstructions from CEMOVIS
Not available
EMPIAR-12835 | biostudies-other
UnknownERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2 mRNA.
Not available
S-EPMC12207402 | biostudies-literature
TranscriptomicsTranscriptional profiling upon knockdown of the RNA-binding protein Unkempt
RNAseq to assess changes in transcript abundance upon knockdown of the RNA-binding protein Unkempt in human SH-SY5Y cell lines.
ORGANISM(S): Homo sapiens 
2015-01-15 | E-MTAB-2277 | biostudies-arrayexpress
UnknownSingle particle cryo EM Data of a human Akirin2 proteasome complex
Not available
EMPIAR-10752 | biostudies-other
UnknownIntravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.
Not available
S-EPMC7734592 | biostudies-literature
Sort   by:  
 Page size