Sort   by:  
 Page size 
TranscriptomicsBulk RNA-Seq of Drosophila melanogaster heads after neuronal Wwox knockdown and AB42 overexpression versus control
Wwox knockdown in Drosophila melanogaster neurons (elav-GAL4) also expressing human AB42 worsens lifespan and climbing as well as increasing AB42 load. To understand these effects further we performed transcriptomics on the same genotypes. Neurons expressing RNAi Control and a LacZ control, RNAi Con...
ORGANISM(S): Drosophila melanogaster 
2025-04-18 | E-MTAB-14948 | biostudies-arrayexpress
TranscriptomicsBulk RNA-Seq of Drosophila melanogaster heads after neuronal Wwox and AB42 overexpression versus control
Neuronal Wwox overexpression using CRISPRa in Drosophila melanogaster also expressing human AB42 can rescue amyloid related phenotypes. To understand how this may occur we performed bulk transcriptomics on day 14 heads from the same genotypes: 1) Control gRNA + lacZ expression control, 2) Control gR...
ORGANISM(S): Drosophila melanogaster 
2025-04-18 | E-MTAB-14949 | biostudies-arrayexpress
TranscriptomicsPlasmodesmal closure triggers stress responses
We generated two independent genetic tools that can induce callose deposition and plasmodesmal closure following estradiol treatment: LexA::Icals3m and LexA::PLUG. We harvested mature leaf tissue at 12h, 24h, 48h and 72h post induction and extracted total RNA
ORGANISM(S): Arabidopsis thaliana 
2026-03-31 | E-MTAB-16776 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of deciduas from pre-eclamptic and normotensive pregnancies
Genome-wide analysis of decidual transcriptome in pre-eclampsia compared with normotensive controls to find differentially expressed genes/pathways. Preeclampsia (PE) is a common and serious pregnancy hypertensive disorder with a strong genetic component. The study aims were to use genome-wide analy...
ORGANISM(S): Homo sapiens 
2015-08-05 | E-GEOD-60438 | biostudies-arrayexpress
TranscriptomicsMicroarray data from YTHDF2-deficient pre-leukemic cells and control pre-leukemic cells
YTHDF2 is overexpressed in a broad spectrum of human acute myeloid leukemias (AML). To study the role of YTHDF2 in leukemia, c-Kit+ cells from foetal livers of Ythdf2fl/fl;Vav-iCre (Ythdf2CKO) and Ythdf2fl/fl (Ythdf2CTL) 14.5 dpc embryos were transduced with Meis1 and Hoxa9 oncogenes and serially re...
ORGANISM(S): Mus musculus 
2019-04-05 | E-MTAB-6783 | biostudies-arrayexpress
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
BAT transcriptome from control and brown adipocyte-specific Rev-erbα/β double knockout mice housed at thermoneutrality or cold-challenged for 6 hours. Brown adipose tissue (BAT) samples were collected from control and brown adipocyte-specific Rev-erbα/β double knockout mice (Ucp1-Cre; Nr1d1/2 fl/fl)...
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17580 | biostudies-arrayexpress
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
Transcriptome from immortalized murine brown adipocytes BMC. Cells were transfected with siRNA construct #1 or construct #2 (pool) or non-targeting control on day 3 of differentiation and harvested on day 7 of differentiation.
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17577 | biostudies-arrayexpress
Sort   by:  
 Page size