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TranscriptomicsLeaps and lulls in the developmental transcriptome of Dictyostelium discoideum
Development of the soil amoeba Dictyostelium discoideum is triggered by starvation. When placed on a solid substrate, the starving solitary amoebae cease growth, communicate via extracellular cAMP, aggregate by tens of thousands and develop into fully integrated multicellular organisms. Early phases...
ORGANISM(S): Dictyostelium discoideum 
2015-04-21 | E-GEOD-61914 | biostudies-arrayexpress
TranscriptomicsBacterial discrimination by Dictyostelid amoebae reveals the complexity of ancient interspecies interactions
Transcriptional profiling of D. discoideum revealed sets of genes whose expression is enriched in amoebae interacting with different species of bacteria, including sets that appear specific to amoebae interacting with Gram(+), or with Gram(-) bacteria. In a genetic screen utilizing the growth of mut...
ORGANISM(S): Dictyostelium discoideum 
2013-05-20 | E-GEOD-46386 | biostudies-arrayexpress
TranscriptomicsTranscriptome conservation of the D. discoideum and D. purpureum developmental programs revealed through RNA-sequencing
Cross species comparison of genomes and transcriptomes is a powerful tool for understanding underlying biological processes, accurate functional classification of genes, and discovery of novel elements. The shift to next-generation sequencing platforms has tremendously accelerated the analysis of ge...
ORGANISM(S): Dictyostelium purpureum 
2010-03-12 | E-GEOD-17637 | biostudies-arrayexpress
Transcriptomicsmonitoring splicing changes in TIA1/TIAL1 double knockdown vs control HeLa cells
Not available
ORGANISM(S): Homo sapiens 
2010-10-26 | E-MTAB-526 | biostudies-arrayexpress
Transcriptomicsabc transporters in Dictyostelium discoideum development
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chemotherapy of cancer patients. There are 68 ABC tran...
ORGANISM(S): Dictyostelium discoideum AX4 
2013-06-14 | E-GEOD-45555 | biostudies-arrayexpress
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