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Tunneling nanotubes (TNTs) connect distant cells and mediate cargo transfer for intercellular communication in physiological and pathological contexts. How the cell controls a common pool of proteins to generate these protrusions spanning length scales beyond those attainable by canonical filopodia ...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-27 | PXD034649 | Pride
To study the effects of scarification on gene expression in the skin we performed microarray analysis on intact skin (control) and skin collected 2 h after scarification. Comparison of microarray data between the two groups showed that 451 probe sets (1.0% of a total 45038 probe sets on the arrays) ...
ORGANISM(S): Mus musculus 
We hypothesized that the transfer of mitochondria via tunneling nanotubes help cancer cells to maintain or boost their metabolism by transferring whole healthy organelles from astrocytes (AS) to tumor cells. To investigate this, we explored the transcriptional changes induced by TNT-dependent transf...
ORGANISM(S): Homo sapiens 
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