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Renal tubular Pck1 knockout mice showed albuminuria.
Chronic kidney disease remains an unmet clinical challenge. It is only detected at advanced stages by current markers. Therefore, early detection of chronic kidney disease is vital. In this study, we profiled the urinary proteome in patients with albuminuria with well-preserved eGFR. We identi-fied ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054170 | Pride
We aim to investigate the role of renal Pck1 on albuminuria. To further development of our gene expression approach to biodosimetry, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish between wild type mice. To el...
ORGANISM(S): Mus musculus 
2023-03-29 | GSE228053 | GEO
Abnormal lactate metabolism is linked to albuminuria and kidney injury in diabetic nephropathy
We aim to investigate the role of renal Sirt1 on albuminuria. To further development of our gene expression approach to biodosimetry, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish between wild type(C57BL/6J) ...
ORGANISM(S): Mus musculus 
2018-03-08 | GSE50140 | GEO
Shroom3-Fyn interaction determines nephrin phosphorylation and Albuminuria in allografts
OVE26 mouse was chosen to study the progressive changes in renal gene expression because it displays the most advanced albuminuria mouse models that assembles advanced human diabetic nephropathy. OVE26 mice induce inflammatory gene expression changes consistent with advanced renal disease, associate...
ORGANISM(S): Mus musculus 
The study aimed to identify potential proteins and pathways involved in hypertension-associated albuminuria by assessing urinary proteomic profiles in black South African participants with combined hypertension and albuminuria compared to those who have neither condition.
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD046441 | Pride
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