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Transcriptomicsm6A in 5’ untranslated regions promotes cap-independent translation of mRNA
N6-methyladenosine (m6A) is a widespread internal RNA modification whose function is poorly understood. Here we report that m6A residues within the 5'UTR promote a novel form of cap-independent translation which is mediated through an interaction between m6A residues and the translation initiation f...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-73405 | biostudies-arrayexpress
TranscriptomicsSystematic discovery of cap-independent translation sequences in human and viral genomesÂ
To investigate gene specificity at the level of translation in both the human genome and viruses we devised a high-throughput bicistronic assay to quantify cap-independent translation. We uncover thousands of novel cap-independent translation sequences and provide insights on the landscape of transl...
ORGANISM(S): synthetic construct 
2015-10-23 | E-GEOD-74277 | biostudies-arrayexpress
UnknownEnhancing cap-independent translation of linear mRNA.
Not available
S-EPMC12532787 | biostudies-literature
GenomicsEngineered circular RNA compatible with complete nucleoside modification and rolling circle translation through a Cap-independent translation enhancer (CITE)
Engineered circular RNA compatible with complete nucleoside modification and rolling circle translation through a Cap-independent translation enhancer (CITE)
PRJNA1295446 | ENA
Unknown5' UTR m(6)A Promotes Cap-Independent Translation.
Not available
S-EPMC4695625 | biostudies-literature
UnknownDifferentiation stage-specific use of cap-independent and cap-dependent translation initiation in hematopoiesis.
Not available
S-EPMC12485689 | biostudies-literature
GenomicsCap-independent translation and a precisely localized RNA sequence enable SARS-CoV-2 to control host translation and escape anti-viral response
Cap-independent translation and a precisely localized RNA sequence enable SARS-CoV-2 to control host translation and escape anti-viral response
PRJNA797428 | ENA
OtherSystematic discovery of cap-independent translation sequences in human and viral genomes 
To investigate gene specificity at the level of translation in both the human genome and viruses, we devised a high-throughput bicistronic assay to quantify cap-independent translation. We uncovered thousands of novel cap-independent translation sequences, and we provide insights on the landscape of...
ORGANISM(S): synthetic construct 
2015-10-23 | GSE74277 | GEO
UnknownThe cap-binding translation initiation factor, eIF4E, binds a pseudoknot in a viral cap-independent translation element.
Not available
S-EPMC3113551 | biostudies-literature
UnknownZuotin, a DnaJ molecular chaperone, stimulates cap-independent translation in yeast.
Not available
S-EPMC2680724 | biostudies-literature
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