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ProteomicsMultilevel analysis of response to plant growth promoting and pathogenic bacteria in Arabidopsis roots and the role of CYP71A27 in this response
Understanding how plants distinguish between commensal and pathogenic microorganisms is one of the major challenges in the plant microbe interaction research. We previously identified a gene encoding CYP71A27 connected to camalexin, which is necessary for a plant growth promoting (PGP) activity of a...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-07-23 | PXD058537 | Pride
Plant-microbe interactions arabidopsis thaliana cyp71a27 camalexin pseudomonas fluorescens burkholderia glumeae plant growth promotion 
UnknownRoot-specific camalexin biosynthesis controls the plant growth-promoting effects of multiple bacterial strains.
Not available
S-EPMC6681745 | biostudies-literature
Genomics
Transcriptomics response of A. thaliana roots to bacteria
PRJNA1196130 | ENA
TranscriptomicsTranscription profiling of mouse models with liver-specific deletion or global hypomorphic expression of the NADPH-cytochrome P450 reductase gene to study molecular mechanisms for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.
NADPH-cytochrome P450 reductase (CPR) is important for the functions of many enzymes, such as microsomal cytochrome P450 (P450) monooxygenases and heme oxygenases. Two mouse models with deficient CPR expression in adults were recently generated in this laboratory: liver-Cpr-null (with liver-specific...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2362 | biostudies-arrayexpress
TranscriptomicsPenetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression (1)
Biallelic mutations of the DNA annealing helicase SMARCAL1 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin, subfamily a-like 1) cause Schimke immuno-osseous dysplasia (SIOD, MIM 242900), an incompletely penetrant autosomal recessive disorder. Using human, Drosophila, and...
ORGANISM(S): Homo sapiens 
2012-04-04 | E-GEOD-35551 | biostudies-arrayexpress
TranscriptomicsAltered gene expression in the small intestine of IE-Cpr-null mice
The NADPH-cytochrome P450 reductase (CPR) is essential for the functioning of microsomal cytochrome P450 (P450) monoxygenases. The biological functions of the CPR-dependent enzymes in the intestine are not known, despite the vast knowledge available on the biochemical properties of the various oxyge...
ORGANISM(S): Mus musculus 
2012-04-10 | E-GEOD-35293 | biostudies-arrayexpress
Transcriptomics3CB-induced gene expression of Pseudomonas putida KT2440/pSL1 in soil (with RNA amplification)
Genome-wide scanning of gene expression by microarray techniques was successfully performed on RNA extracted from a sterilized soil inoculated with Pseudomonas putida KT2440/pSL1, which contains a chloroaromatic degrading plasmid, in the presence or absence of 3-chlorobenzoic acid (3CB). The genes s...
ORGANISM(S): Pseudomonas putida KT2440 
2011-03-29 | E-GEOD-28215 | biostudies-arrayexpress
TranscriptomicsExpression profiling of the retinal pigment epithelium in zebrafish smarca4 mutant
Purpose: The purpose of this study was to develop a framework for analyzing RPE expression profiles from zebrafish eye mutants. Methods: The fish model we used was smarca4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4), a retinal dystrophic muta...
ORGANISM(S): Danio rerio 
2014-01-03 | E-GEOD-50241 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila Hr39 mutant females reveals the sf1-related nuclear hormone receptor hr39 regulates Drosophila female reproductive tract development and function
The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductive development and regulates the transcription of steroid-modifying cytochrome P450 genes. We find that the SF1-related Drosophila nuclear hormone receptor HR39 is also essential for sexual development. In...
ORGANISM(S): Drosophila melanogaster 
2008-06-11 | E-GEOD-10264 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat liver to examine aging induced alterations in hepatic gene expression
Toxicokinetic and metabolism studies are considered crucial to dose setting and interpretation of data from rodent carcinogenicity studies. The metabolism and distribution studies are usually conducted in 6 to 8 week old rodents. However cancer studies generally involve exposures from 6 weeks of a...
ORGANISM(S): Rattus norvegicus 
2008-06-18 | E-GEOD-4270 | biostudies-arrayexpress
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