Sort   by:  
 Page size 
GenomicsCytosine methylation and hydroxymethylation mark DNA for elimination in Oxytricha trifallax.
We report the existence of both methylcytosine and hydroxymethylcytosine in the genomic DNA of the ciliate Oxytricha trifallax during its genome rearrangement process. These modifications are dynamically added, de novo, to sequences targeted for elimination and are not present after the rearrangemen...
ORGANISM(S): Oxytricha trifallax 
2012-09-26 | E-GEOD-41060 | biostudies-arrayexpress
MetabolomicsThe genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitides

Cyclic peptides are reported to have antibacterial, antifungal and other bioactivities. Orbitides are a class of cyclic peptide that are small, head-to-tail cyclized, composed of proteinogenic amino acids, and lack disulfide bonds; they are also known in several genera of the plant family Rutacea...

2020-10-14 | MTBLS1963 | MetaboLights
GenomicsRepressive and active histone methylation mark distinct promoters in human and mouse spermatozoa (Illumina)
In higher eukaryotes, histone methylation is involved in the maintenance of cellular identity during somatic development. During spermatogenesis, Since most nucleosomes are replaced by protamines during spermatogenesis . Iit is therefore unclear whether if histone modifications function in paternal ...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-19889 | biostudies-arrayexpress
TranscriptomicsRepressive and active histone methylation mark distinct promoters in human and mouse spermatozoa
This SuperSeries is composed of the following subset Series: GSE13863: Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa (Nimblegen) GSE19889: Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa (Illumina) Re...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-19892 | biostudies-arrayexpress
UnknownMirror-mark tests performed on jackdaws reveal potential methodological problems in the use of stickers in avian mark-test studies.
Not available
S-EPMC3903501 | biostudies-literature
TranscriptomicsPolycomb repressive complex 2-dependent and M-bM-^@M-^Sindependent functions of Jarid2 in transcriptional regulation in Drosophila
This SuperSeries is composed of the following subset Series: GSE33546: Polycomb repressive complex 2-dependent and M-bM-^@M-^Sindependent functions of Jarid2 in transcriptional regulation in Drosophila [ChIP-Seq] GSE36038: Polycomb repressive complex 2-dependent and M-bM-^@M-^Sindependent functions ...
ORGANISM(S): Drosophila melanogaster 
2012-02-23 | E-GEOD-36039 | biostudies-arrayexpress
UnknownA body shape index and vascular structure and function in Spanish adults (MARK study): A cross-sectional study.
Not available
S-EPMC6392544 | biostudies-literature
GenomicsR-loops induce repressive chromatin marks over mammalian gene terminators
The formation of R-loops is a natural consequence of the transcription process, caused by invasion of the DNA duplex by nascent transcripts. These structures have been considered rare transcriptional by-products with potential harmful effects on genome integrity, due to the fragility of the displace...
ORGANISM(S): Homo sapiens 
2014-09-29 | E-GEOD-59878 | biostudies-arrayexpress
GenomicsGenome-wide maps of Foxa2 binding sites in mouse embryonic stem cell-derived definitive endoderm cells
Foxa2 is required for endoderm differentiation into hepatic lineage. The mechanism of activation for Foxa2 during this developmental process has not been elucidated yet. We established an in vitro system to guide ES cells differentiating into definitive endoderm (DE) cells and the following DE cells...
ORGANISM(S): Mus musculus 
2012-08-29 | E-GEOD-40423 | biostudies-arrayexpress
TranscriptomicsMonovalent and unpoised status of most genes in undifferentiated cell-enriched Drosophila testis
We use male gonads isolated from a Drosophila strain that allows us to obtain enough cells at their primitive status as the starting material to study the endogenous chromatin structure of undifferentiated cells using ChIP-seq. We integrate the ChIP-seq data with RNA-seq data that measures the trans...
ORGANISM(S): Drosophila melanogaster 
2010-04-16 | E-GEOD-19325 | biostudies-arrayexpress
Sort   by:  
 Page size