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UnknownSpecific Disease Knowledge as Predictor of Susceptibility to Availability Bias in Diagnostic Reasoning: a Randomized Controlled Experiment.

Background

Bias in reasoning rather than knowledge gaps has been identified as the origin of most diagnostic errors. However, the role of knowledge in counteracting bias is unclear.

Objective

To examine whether knowledge of discriminating features (findings that discriminate between l...
S-EPMC7947124 | biostudies-literature
UnknownCOVIDiSTRESS diverse dataset on psychological and behavioural outcomes one year into the COVID-19 pandemic.
During the onset of the COVID-19 pandemic, the COVIDiSTRESS Consortium launched an open-access global survey to understand and improve individuals' experiences related to the crisis. A year later, we extended this line of research by launching a new survey to address the dynamic landscape of the pan...
S-EPMC9213519 | biostudies-literature
UnknownARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia.

Background

Acute leukemia in early age (EAL) is characterized by acquired genetic alterations such as MLL rearrangements (MLL-r). The aim of this case-controlled study was to investigate whether single nucleotide polymorphisms (SNPs) of IKZF1, ARID5B, and CEBPE could be related to the onset ...
S-EPMC3948138 | biostudies-literature
UnknownSearching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries.

Background

Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignancies in humans. The average 5-year survival rate is one of the lowest among aggressive cancers, showing no significant improvement in recent years. When detected early, HNSCC has a good prognosis, but ...
S-EPMC2629771 | biostudies-literature
UnknownGlobal gene expression profiling of oral cavity cancers suggests molecular heterogeneity within anatomic subsites.

Background

Oral squamous cell carcinoma (OSCC) is a frequent neoplasm, which is usually aggressive and has unpredictable biological behavior and unfavorable prognosis. The comprehension of the molecular basis of this variability should lead to the development of targeted therapies as well as...
S-EPMC2632665 | biostudies-literature
UnknownSustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023.
Since autumn 2022, observed numbers of paediatric invasive group A Streptococcus infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the dominant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A num...
S-EPMC10486195 | biostudies-literature
UnknownThe globalizability of temporal discounting.
Economic inequality is associated with preferences for smaller, immediate gains over larger, delayed ones. Such temporal discounting may feed into rising global inequality, yet it is unclear whether it is a function of choice preferences or norms, or rather the absence of sufficient resources for im...
S-EPMC9584811 | biostudies-literature
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