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UnknownReal-world efficacy and safety of immunochemotherapy in cold agglutinin-mediated autoimmune haemolytic anaemia.
Not available
S-EPMC12710113 | biostudies-literature
UnknownComparison of diagnostic algorithms used in guidelines on nutritional anaemias in adults.

Background

Anaemia is highly prevalent and commonly caused by nutritional deficiencies. Guidelines often include an algorithm to find the underlying cause. Here, we compared diagnostic algorithms and suggested laboratory tests for anaemia in clinical practice guidelines in countries with sim...
S-EPMC12494270 | biostudies-literature
UnknownRisk factors for development and progression of diabetic retinopathy in Dutch patients with type 1 diabetes mellitus.

Purpose

To investigate risk factors for the development and progression of diabetic retinopathy (DR) and long-term visual outcomes in Dutch patients with type 1 diabetes mellitus (T1DM).

Methods

Cumulative incidences were calculated for DR, vision-threatening DR (VTDR), defined as (pr...
S-EPMC6174939 | biostudies-literature
TranscriptomicsChromatin position effects assayed by thousands of reporters integrated in parallel (RNA-Seq)
Reporter genes integrated into the genome are a powerful tool to reveal effects of regulatory elements and local chromatin context on gene expression. However, so far such reporter assays have been of low throughput. Here we describe a multiplexing approach for the parallel monitoring of transcripti...
ORGANISM(S): Mus musculus 
2013-08-16 | E-GEOD-48607 | biostudies-arrayexpress
TranscriptomicsChromatin position effects assayed by thousands of reporters integrated in parallel (mPGK TRIP pools)
Reporter genes integrated into the genome are a powerful tool to reveal effects of regulatory elements and local chromatin context on gene expression. However, so far such reporter assays have been of low throughput. Here we describe a multiplexing approach for the parallel monitoring of transcripti...
ORGANISM(S): Mus musculus 
2013-08-16 | E-GEOD-48608 | biostudies-arrayexpress
TranscriptomicsChromatin position effects assayed by thousands of reporters integrated in parallel (tet-Off TRIP pools)
Reporter genes integrated into the genome are a powerful tool to reveal effects of regulatory elements and local chromatin context on gene expression. However, so far such reporter assays have been of low throughput. Here we describe a multiplexing approach for the parallel monitoring of transcripti...
ORGANISM(S): Mus musculus 
2013-08-16 | E-GEOD-49806 | biostudies-arrayexpress
TranscriptomicsChromatin position effects assayed by thousands of reporters integrated in parallel (cell lines with mPGK IRs)
Reporter genes integrated into the genome are a powerful tool to reveal effects of regulatory elements and local chromatin context on gene expression. However, so far such reporter assays have been of low throughput. Here we describe a multiplexing approach for the parallel monitoring of transcripti...
ORGANISM(S): Mus musculus 
2013-08-16 | E-GEOD-49807 | biostudies-arrayexpress
UnknownDeep learning for the detection of benign and malignant pulmonary nodules in non-screening chest CT scans.

Background

Outside a screening program, early-stage lung cancer is generally diagnosed after the detection of incidental nodules in clinically ordered chest CT scans. Despite the advances in artificial intelligence (AI) systems for lung cancer detection, clinical validation of these systems ...
S-EPMC10611755 | biostudies-literature
UnknownProspective Study of Drug-induced Interstitial Lung Disease in Advanced Breast Cancer Patients Receiving Everolimus Plus Exemestane.

Background

Everolimus-related interstitial lung disease (ILD) (also: pneumonitis) poses a difficulty for physicians, as it is hard to discriminate ILD from other causes of respiratory symptoms and to decide on safe treatment continuation.

Objective

We investigated the capability of pu...
S-EPMC6684805 | biostudies-literature
UnknownEffectiveness and safety of tofacitinib for ulcerative colitis: two-year results of the ICC Registry.

Background

Tofacitinib is an oral Janus kinase (JAK) inhibitor and is registered for the treatment of ulcerative colitis (UC). The effectiveness of tofacitinib has been evaluated up to 12 months of treatment.

Aim

The aim of this study was to assess the effectiveness and safety of 24 m...
S-EPMC10092078 | biostudies-literature
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