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ProteomicsExposure of Mycobacterium tuberculosis to thioridazine alters the cell envelope permeability; an alternative mechanism for the synergistic effects with other antibiotics
The emergence of multidrug resistant tuberculosis and the increasing level of resistance urges the search for alternative drugs in treatment. Several neuroleptics, like thioridazine, reveal activity against Mycobacterium tuberculosis. Thioridazine was even successfully applied in compassionate thera...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2016-07-06 | PXD001208 | Pride
Proteomics Mycobacterium tuberculosis Thioridazine Lc-ms/ms 
ProteomicsDisclosure of selective advantages in the “modern” sublineage of the Mycobacterium tuberculosis Beijing genotype family by quantitative proteomics.
Using two different comparative proteomic approaches we studied the M. tuberculosis Beijing genotype.
ORGANISM(S): Mycobacterium tuberculosis C 
2014-07-16 | PXD000931 | Pride
Mycobacterium tuberculosis Ltq-ft Comparative proteomics 
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