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PRDM9 specifies the sites of meiotic DNA double strand break that initiate meiotic recombination in mice and humans. PRDM9 is known to bind to specific DNA sequences with its DNA binding domain, to induce H3K4me3 and H3K36me3 to adjacent nucleosomes through its methyltransferase activity, and to rec...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-03 | PXD017337 | Pride
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Understanding the extent of genomic transcription and its functional relevance is a central goal in genomics research. However, detailed genome€wide investigations of transcriptome complexities in major mammalian organs  and  their  underlying  cellular sources, transcriptional mechanisms, and func...
ORGANISM(S): Mus musculus 
Understanding  the  extent  of  genomic  transcription  and  its  functional  relevance  is  a  central  goal  in  genomics research. However, detailed genome‐wide investigations of transcriptome complexities in major mammalian organs  and  their  underlying  cellular  sources,  transcriptional  mec...
ORGANISM(S): Mus musculus 
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