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TranscriptomicsDepletion of beta1 integrins in triple negative breast cancer cells causes extensive alterations in gene expression profiles
Interactions with the extracellular matrix (ECM) through integrin adhesion receptors provide cancer cells with physical and chemical cues that act in concert with growth factors to support survival and proliferation. Preclinical studies testing beta1 integrin antagonists in (breast) cancer models h...
ORGANISM(S): Mus musculus 
2014-02-11 | E-MTAB-2185 | biostudies-arrayexpress
TranscriptomicsDe novo comparative transcriptome analyses of strawberry (Fragaria vesca) genotypes in response to Phytophthora cactorum.
In this RNA-seq study, we compared the transcriptome of three Fragaria vesca genotypes in response to Phytophthora cactorum. The goal of our study was to dissect the resistance mechanism of the diploid strawberry (F. vesca) that are resistant to P. cactorum. A susceptible genotype (NCGR1218) and two...
ORGANISM(S): Fragaria vesca 
2023-01-01 | E-MTAB-12152 | biostudies-arrayexpress
TranscriptomicsGlobal hepatic gene expression in rainbow trout exposed to sewage effluents
Effluents from sewage treatment plants contain a mixture of micropollutants with the potential of harming aquatic organisms. Thus, addition of advanced treatment techniques to complement existing conventional methods has been proposed. Some of the advanced techniques could, however, potentially prod...
ORGANISM(S): Oncorhynchus mykiss 
2012-05-09 | E-GEOD-37574 | biostudies-arrayexpress
UnknownBacterial community dynamics and activity in relation to dissolved organic matter availability during sea-ice formation in a mesocosm experiment.
Not available
S-EPMC3937737 | biostudies-literature
ProteomicsLabel-free based quantitative proteomics analysis of primary neonatal porcine Leydig cells exposed to the persistent contaminant 3-methylsulfonyl-DDE
Evidence that persistent environmental pollutants may target the male reproductive system is increasing. The male reproductive system is regulated by secretion of testosterone by testicular Leydig cells, and perturbation of Leydig cells function may have ultimate consequences. 3-methylsulfonyl-DDE (...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2016-01-05 | PXD003165 | Pride
Endocrine disruption Proteomics 3-methylsulfonyl-dde Ipa Leydig cells Sus scrofa Persistent organic pollutants Steroidogenesis 
TranscriptomicsTranscription profiling of heptatocytes from mice given a high-copper diet
In order to study the physiological consequences of a high-copper diet on hepatic gene expression, 6 mM CuCl2 was added to the drinking water for a period of 1 month. After this period, livers of seven control mice and eight copper-treated mice were isolated and were subjected to microarray analysis...
ORGANISM(S): Mus musculus 
2007-06-01 | E-MEXP-745 | biostudies-arrayexpress
TranscriptomicsInduced inflammation perturbs testis formation in zebrafish
Effect of heat-killed E. coli on zebrafish sex determination.
ORGANISM(S): Danio rerio 
2012-06-08 | E-MEXP-3249 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to zinc limitation in chemostat cultures
Zinc is indispensable for the catalytic activity and structural stability of many proteins, and its deficiency can have severe consequences for microbial growth in natural and industrial environments. For example, Zn depletion in wort negatively affects beer fermentation and quality. Several studies...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-15 | E-GEOD-8035 | biostudies-arrayexpress
MetabolomicsIdentifying metabolic alterations associated with coral growth anomalies using 1H NMR metabolomics
Coral growth anomalies (GAs) are tumor-like protrusions that are detrimental to coral health, impacting both the coral skeleton and soft tissues. These lesions are increasingly found throughout the tropics and are commonly associated with high human population density, yet little is known about the ...
2021-06-15 | MTBLS2424 | MetaboLights
GenomicsPrecipitation is the main axis of tropical plant phylogenetic turnover across space and time
Precipitation is the main axis of tropical plant phylogenetic turnover across space and time
PRJEB52227 | ENA
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