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TranscriptomicsHoxd genes and fiber type-specific markers specify adult mouse muscle type in a diet-independent way
Introduction: The mouse skeletal muscle is composed of four distinct fiber types that differ in contractile function, number of mitochondria and metabolism. Every muscle group has a specific composition and distribution of the four fiber types. Until now, three genes (CnA, PGC1α and PPARδ) are ident...
ORGANISM(S): Mus musculus 
2010-09-03 | E-GEOD-18127 | biostudies-arrayexpress
TranscriptomicsA high fat diet causes obesity and insulin resistance in mice, but induces small changes in the muscle transcriptome
An 8-week high fat palm oil diet causes obesity and insulin resistance in C57BL/6J mice, but induces only small changes in the muscle transcriptome. Introduction: The metabolic syndrome (MS) is a cluster of metabolic abnormalities linked to an increased risk of type 2 diabetes and cardiovascular dis...
ORGANISM(S): Mus musculus 
2010-08-10 | E-GEOD-17576 | biostudies-arrayexpress
TranscriptomicsShort-term high fat-feeding results in morphological and metabolic adaptations in the skeletal muscle of C57BL/6J mice
The prevalence of the metabolic syndrome (MS) is rapidly increasing all over the world. Consequently, there is an urgent need for more effective intervention strategies. Both animal and human studies indicate that lipid oversupply to skeletal muscle can result in insulin resistance which is one of t...
ORGANISM(S): Mus musculus 
2007-11-30 | E-GEOD-8524 | biostudies-arrayexpress
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