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TranscriptomicsListening in on a bacterial/fungal dialog: transcriptional profiling of an antagonistic interaction
The genus Collimonas consists of soil bacteria that are well known for their antifungal activity and for mycophagy, i.e. the ability to grow at the expense of living fungi. The aim of the current study was to gain a better understanding of the mechanisms of antagonism of Collimonas bacteria towards ...
ORGANISM(S): Collimonas fungivorans 
2011-06-20 | E-MTAB-350 | biostudies-arrayexpress
TranscriptomicsGene expression data from children diagnosed with ALL in vitro sensitive or resistant to prednisolone
Although the prognosis for childhood Acute Lymphoblastic Leukemia (ALL) in general has improved tremendously over the last decades, the survival chances for infants (<1 year of age) with ALL remains poor. A major obstacle hampering successful treatment results in infant ALL is cellular resistance to...
ORGANISM(S): Homo sapiens 
2009-12-15 | E-GEOD-19143 | biostudies-arrayexpress
TranscriptomicsHigh VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia.
High VEGFC mRNA expression of AML blasts is related to increased in vitro and in vivo drug resistance. The prognostic significance of VEGFC on long-term outcome and its associated gene expression profiles remain to be defined. We studied the effect of VEGFC on treatment outcome and investigated gene...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-22056 | biostudies-arrayexpress
MetabolomicsExploring the Interspecific Interactions and the Metabolome of the Soil Isolate Hylemonella gracilis
Analysis of aquatic microbial communities revealed that parts of its diversity consist of bacteria with cell sizes of ~0.1 μm. Such bacteria can show genomic reductions and metabolic dependencies with other bacteria. So far, no study investigated if such bacteria exist in terrestrial environments e....
2022-12-14 | MTBLS5841 | MetaboLights
TranscriptomicsIdentification of BABY BOOM downstream targets
A glucocorticoid-regulated BBM protein (35S:BBM-GR) was used in combination with microarray analysis to identify genes directly activated by BBM. We employed the system described by (Lloyd et al., 1994) in which dexamethasone (DEX) and cycloheximide (CHX) are applied together to respectively, induce...
ORGANISM(S): Arabidopsis thaliana 
2010-06-25 | E-GEOD-3399 | biostudies-arrayexpress
TranscriptomicsGene expression profiles associated with pediatric relapsed AML
In high income countries 90% of the patients achieve complete remission after induction chemotherapy. However, 30-40% of these patients suffer from relapse. These patients face a dismal prognosis, as the majority (>60%) of relapsed patients die within 5 years. As a result, outcome for pediatric acut...
ORGANISM(S): Homo sapiens 
2015-05-07 | E-GEOD-52891 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast to investigate the involvement of Snf7 and Rim101 in regulation of TIR1 and anaerobically up-regulated genes
Despite the scientific and applied interest in anaerobic metabolism of Saccharomyces cerevisiae, not all genes whose transcription is up-regulated under anaerobic conditions have yet been linked to known transcription factors. Experiments with a reporter construct in which the promoter of the anaero...
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-02 | E-GEOD-18128 | biostudies-arrayexpress
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
TranscriptomicsTransduced cord blood CD34+ cells with empty vector, AML1-ETO and ETV6-RUNX1
Mononuclear cells were isolated from umbilical cord blood (UCB) using Lymphoprep sucrose-gradient centrifugation (1.077 g/ml, Nycomed Pharma, Oslo, Norway). Immunomagnetic cell separation, using magnetic beads coated with CD34 antibodies (Miltenyi Biotec, Gladbach, Germany), was performed to isolate...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-3466 | biostudies-arrayexpress
UnknownAutophagy inhibition as a potential future targeted therapy for ETV6-RUNX1-driven B-cell precursor acute lymphoblastic leukemia.
Not available
S-EPMC6442983 | biostudies-literature
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