Sort   by:  
 Page size 
MetabolomicsPlasma metabolomic profiling reveals altered metabolic pathways associated with idiopathic hyperaldosteronism
This study investigated plasma metabolic alterations associated with idiopathic hyperaldosteronism using untargeted liquid chromatography coupled with high-resolution mass spectrometry. Plasma samples from patients with idiopathic hyperaldosteronism and healthy controls were analyzed using a Vanquis...
2026-08-07 | MTBLS15210 | MetaboLights
MetabolomicsOmics data integration allows the identification of an idiopathic Parkinson’s disease signature
The vast majority of Parkinson’s disease cases are idiopathic. Unclear ethiology and multifactorial nature complicate the comprehension of disease pathogenesis. Identification of early transcriptomic and metabolic alterations consistent across different idiopathic Parkinson’s disease (IPD) patients ...
2026-03-16 | MTBLS7740 | MetaboLights
MetabolomicsPlasma metabolome reveals altered oxidative stress, inflammation, and amino acid metabolism in dogs with idiopathic epilepsy.

OBJECTIVE: Idiopathic epilepsy (IE) is the most common chronic neurological disease in dogs, and an established natural animal model for human epilepsy types with genetic and unknown etiology. However, the metabolic pathways underlying IE remain largely unknown. METHODS: Plasma samples of healthy...

2025-07-02 | MTBLS10915 | MetaboLights
MetabolomicsSeminal lipid depletion and gut microbiome–metabolome alterations in men with gonadotropin-treated idiopathic hypogonadotropic hypogonadism: an integrated multi-omics study
This study investigated seminal plasma lipid alterations and gut microbiome–metabolome changes in men with gonadotropin-treated idiopathic hypogonadotropic hypogonadism. Seminal plasma metabolomics, fecal metagenomic sequencing, and fecal metabolomics were performed in patients and healthy controls....
2026-07-20 | MTBLS15080 | MetaboLights
MetabolomicsMetabolomic Changes in Idiopathic and GBA1 Parkinson’s Disease

Background Variants in the β-glucocerebrosidase (GBA1) gene are the commonest genetic risk factor for Parkinson Disease (PD). Here, we use mass spectrometry based metabolomics to analyse serum and sebum samples from 50 genotyped participants and find differences in lipid and sugar reg...

2025-09-18 | MTBLS10743 | MetaboLights
MetabolomicsMetabolic signature of idiopathic inflammatory myopathy
Not available
ORGANISM(S): Homo sapiens 
ST002196 | MetabolomicsWorkbench
MetabolomicsFunctional Remodeling of the Gut Microbiome and Metabolome in Primary Idiopathic Male Infertility

Abstract

Background: Primary idiopathic male infertility (PIMI) is a complex condition with unclear biological mechanisms. Increasing evidence indicates that gut microbiome-derived functional and metabolic alterations can influence host physiological processes, yet microbiome-associated fun...

2026-04-07 | MTBLS13886 | MetaboLights
MetabolomicsMetabolic Markers of Methotrexate Response in Juvenile Idiopathic Arthritis
Not available
ORGANISM(S): Homo sapiens 
ST001815 | MetabolomicsWorkbench
MetabolomicsLongitudinal Characterization of the Fecal Metabolome in Dogs with Idiopathic Inflammatory Bowel Disease
Not available
ORGANISM(S): Canis lupus familiaris 
ST001247 | MetabolomicsWorkbench
TranscriptomicsPeripheral Blood Mononuclear Cell Gene Expression Profiles May Predict Poor Outcome in Idiopathic Pulmonary Fibrosis
Background: In this study we aimed to identify peripheral blood mononuclear cell (PBMC) gene expression profiles predictive of poor outcomes in idiopathic pulmonary fibrosis (IPF) Methods: Microarray analyses of PBMC were performed in 120 patients from discovery (n=45) and replication cohorts (n=7...
ORGANISM(S): Homo sapiens 
2013-10-15 | E-GEOD-28221 | biostudies-arrayexpress
Sort   by:  
 Page size