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UnknownInvestigating the effect of tenuigenin on LPS-induced HPMEC dysfunction by inhibiting SRC activation based on network pharmacology and molecular docking.
Not available
S-EPMC12481841 | biostudies-literature
ProteomicsTMT-based quantitative proteomics reveals the protective mechanism of Tenuigenin after experimental intracerebral hemorrhage in mice
Tenuigenin (TNG), an extract obtained from Polygalae Radix, possesses anti-inflammatory,anti-oxidant, neuro-protective properties. However, the potential mechanism of TNG on intracerebral hemorrhage (ICH) has not been well studied. Therefore, in this study, we aimed to identify the prospective mecha...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-15 | PXD045270 | Pride
Mice tenuigenin  intracerebral hemorrhage 
UnknownTenuigenin protects dopaminergic neurons from inflammation-mediated damage induced by the lipopolysaccharide.
Not available
S-EPMC6493587 | biostudies-literature
UnknownTenuigenin promotes the osteogenic differentiation of bone mesenchymal stem cells in vitro and in vivo.
Not available
S-EPMC5269466 | biostudies-literature
Genomics
Tenuigenin regulates succinylation via SIRT5 for suppressing the tumourigenicity of hepatocellular carcinoma cells
PRJNA1007232 | ENA
UnknownTenuigenin attenuates α-synuclein-induced cytotoxicity by down-regulating polo-like kinase 3.
Not available
S-EPMC6493467 | biostudies-literature
MetabolomicsThe synergistic growth promoting mechanism of ""internal and external"" microbiota for maize growth mediated by dark septate endophytes

BACKGROUND: The coevolution and interaction between plants and microorganisms have long been a subject of significant research interest. Dark septate endophytes (DSE) have garnered great attention in contemporary research due to their functional diversity, in vitro cultivation ab...

2023-12-15 | MTBLS8903 | MetaboLights
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