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ProteomicsCellular Validation of Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2
Ubiquitin thioesterase OTUB2, a cysteine protease from the ovarian tumor (OTU) deubiquitinase superfamily, is associated with enhanced expression during tumor progression and metastasis. Development of OTUB2 inhibitors is therefore believed to be therapeutically important, yet potent and selective s...
ORGANISM(S): Homo sapiens (Human) 
2023-06-27 | PXD041346 | Pride
Otub2 Small-molecule inhibitor Monoubiquitination 
GenomicsGenome-wide assessment of differential roles for p300 and CBP in transcription regulation
Through ChIP-Seq analysis with the Illumina Whole Genome Analyzer, we identify binding sites for P300 (EP300) and CBP (CREBBP) in Human glioblastoma T98G cells that were cell cycle synchronized before and after stimulation. In our analysis, we focused on the identification of genes differentially bo...
ORGANISM(S): Homo sapiens 
2010-03-30 | E-GEOD-21026 | biostudies-arrayexpress
UnknownT cell activation markers CD38 and HLA-DR indicative of non-seroconversion in anti-CD20-treated patients with multiple sclerosis following SARS-CoV-2 mRNA vaccination.
Not available
S-EPMC11347213 | biostudies-literature
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