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TranscriptomicsSystems biology analysis unravels complementary action of combined Rosuvastatin and Ezetimibe therapy
Transcriptomics analysis to understand both efficacy and side effects of a cholesterol lowering drug combination therapy based on biological pathways and molecular processes affected by each drug alone or in combination. We have treated ApoE*3Leiden mice, a humanized atherosclerosis model with a uni...
ORGANISM(S): Mus musculus 
2013-02-27 | E-GEOD-38688 | biostudies-arrayexpress
TranscriptomicsA systems biology approach to understand the pathophysiological mechanisms of cardiac pathological hypertrophy associated with rosiglitazone
Cardiac pathological hypertrophy is associated with a significantly increased risk of coronary heart disease and has been observed in diabetic patients treated with rosiglitazone, whereas most published studies do not suggest a similar increase in risk of cardiovascular events in pioglitazone-treate...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-48977 | biostudies-arrayexpress
TranscriptomicsSupervised Lowess normalization of comparative genome hybridization data: application to lactococcal strain comparisons.
Background Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. In aCGH data, systematic errors are comparable to those occurring in transcriptome data. However, especially for microbes, an additional source of variation exists: ...
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 
2008-07-19 | E-GEOD-9039 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of ApoE3Leiden mice exposed to high doses of cholesterol and one of three atherosclerosis drugs rosuvastatin, fenofibrate and T0901317 in order to compare atherosclerosis therapeutics
A study of the effects of dietary cholesterol and drug treatment on atherosclerotic lesion development using ApoE3Leiden mice
ORGANISM(S): Mus musculus 
2011-06-25 | E-MEXP-3282 | biostudies-arrayexpress
UnknownFrom Burden to Empowerment. Patient-Reported Influencing Factors on Participation in Shared Decision Making in Oncology, a Meta-Study.
Not available
S-EPMC12260273 | biostudies-literature
TranscriptomicsTranscription profiling of white adipose tissue from Lldlr-/- and Lldlr-/-Mif-/- mice
MIF deficiency reduces chronic inflammation in white adipose tissue and impairs development of insulin resistance, glucose intolerance and associated atherosclerotic disease
ORGANISM(S): Mus musculus 
2009-06-19 | E-TABM-524 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of ApoE3Leiden mice exposed to varying doses of cholesterol to examine the effects of dietary cholesterol on liver homeostasis in the context of early atherosclerotic lesion development
A dose-response study of the effects of dietary cholesterol on liver homeostasis in the context of early atherosclerotic lesion development using ApoE3Leiden mice
ORGANISM(S): Mus musculus 
2007-10-13 | E-TABM-253 | biostudies-arrayexpress
UnknownSensitivity of dose-volume indices to computation settings in high-dose-rate prostate brachytherapy treatment plan evaluation.
Not available
S-EPMC6448172 | biostudies-literature
TranscriptomicsTranscription profiling of peripheral blood mononuclear cells and adipose tissue from overweight men fed an anit-inflammatory dietary mix
It was hypothesized that specific dietary components are able to reduce low grade inflammation, as well as metabolic stress and oxidative stress in overweight men
ORGANISM(S): Homo sapiens 
2010-03-25 | E-TABM-871 | biostudies-arrayexpress
UnknownCommunication at work: A survey to explore the relationships between healthcare providers' communication competence and professional quality of life in neonatal care.
Not available
S-EPMC11437867 | biostudies-literature
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