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Genomicsena-DATASET-DKFZ-03-08-2020-18:14:14:560-2122 - samples
To investigate the immune response and mechanisms associated with severe COVID-19, we performed single-cell RNA-seq on nasopharyngeal and bronchial samples from 19 clinically well-characterized patients with moderate or critical disease and from 5 healthy controls. We identified airway epithelial ce...
EGAD00001006339 | EGA
2019 novel coronavirus infection 2019-nCoV infection coronavirus disease 2019 COVID-19 SARS-coronavirus 2 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 
GenomicsSingle-cell analysis of airway samples identifies immune cell activation correlating with COVID-19 disease severity
To investigate the immune response and mechanisms associated with severe COVID-19, we performed single-cell RNA-seq on nasopharyngeal and bronchial samples from 19 clinically well-characterized patients with moderate or critical disease and from 5 healthy controls. We identified airway epithelial ce...
EGAS00001004481 | EGA
2019 novel coronavirus infection 2019-nCoV infection coronavirus disease 2019 COVID-19 SARS-coronavirus 2 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 
TranscriptomicsLentiviral vector-based insertional mutagenesis identifies new clinically relevant candidate cancer genes involved in the pathogenesis of hepatocellular carcinoma
We devised a novel insertional mutagenesis approach based on lentiviral vectors to induce hepatocellular carcinoma in three mouse models and identified four novel cancer initiating genes. Two genes are the well characterized Braf and Sos1, while the other two are Fign, encoding an AAA ATPase whose f...
ORGANISM(S): Homo sapiens 
2015-02-19 | E-GEOD-35986 | biostudies-arrayexpress
GenomicsSHH medulloblastoma samples
Sequencing data of human SHH medulloblastoma samples
EGAS00001000607 | EGA
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-12:36:36:554-60 - samples
The data set contains bam files aligned using bwa-0.7.8 mem -t 8 -R.
EGAD00001003827 | EGA
GenomicsBIH COVID-19 airway single-cell data access committee.
Data Access Committee EGAC00001001627
EGAC00001001627 | EGA
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-13:02:22:609-63 - samples
This dataset contains paired fastq files for LMS tumor samples
EGAD00001003828 | EGA
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-13:14:23:391-67 - samples
The data set contains paired end fastq files for whole exome sequencing data for Leiomyosarcoma tumor and control samples
EGAD00001003829 | EGA
GenomicsIntegrative genomic and transcriptomic analysis of adult leiomyosarcoma (HIPO-028, HIPO-018, HIPO-021)
Leiomyosarcoma (LMS) is an aggressive mesenchmyal malignancy with few therapeutic options. The mechanisms underlying LMS development, including clinically actionable genetic vulnerabilities, are largely unknown. We performed genomic and transcriptomic profiling of a large cohort of LMS tumors and id...
EGAS00001002437 | EGA
GenomicsDKFZ-HIPO Data Access Committee of Heidelberg Center for Personalized Oncology
Data Access Committee EGAC00001000452
EGAC00001000452 | EGA
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