Models

Dataset Information

Theinmozhi2018 - Mechanism of PD1 inhibiting TCR signaling in Tumor immune regulation


ABSTRACT: Its a Deterministic ODE model showcasing mechanism of PDL1 induced TCR and CD38 signalling inhibition. The model also contains the LCK activation and inactivation phenomenon dependent on the particular phosphorylation site. This model is relevant in immunotherapy.

SUBMITTER: Krishna Kumar Tiwari  

PROVIDER: BIOMD0000000724 | BioModels | 2024-09-02

REPOSITORIES: BioModels

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