Nikolaev2019 - Immunobiochemical reconstruction of influenza lung infection-melanoma skin cancer interactions

ABSTRACT: This is a mathematical mechanistic immunobiochemical model that incorporates T cell pathways that control programmed cell death protein 1 (PD-1) expression. A core component of the model is a kinetic motif, termed a PD-1 Double Incoherent Feed-Forward Loop (DIFFL), which reflects known interactions between IRF4, Blimp-1, and Bcl-6.

SUBMITTER: Johannes Meyer  

PROVIDER: BIOMD0000000865 | BioModels | 2024-09-02

REPOSITORIES: BioModels