Transcription profiling of pig aortic endothelium taken from regions of disturbed and undisturbed flow

ABSTRACT: This study investigates the role of endothelial cell (EC) gene expression in the focal origin of atherosclerosis, particularly in response to local hemodynamics. Differential gene expression was profiled in EC isolated from athero-susceptible and athero-protected regions of the normal pig aorta. Specifically, a region of disturbed flow (DF, the inner aortic arch) was compared to a region of undisturbed flow (UF, descending thoracic aorta). Linearly amplified RNA was used to screen nylon filter arrays of 13,824 human cDNAs.

ORGANISM(S): Sus scrofa

SUBMITTER: unknown unknown 

PROVIDER: E-CBIL-17 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress