Polyphosphate affects gene expression and viability of Porphyromonas gingivalis W83

ABSTRACT: Polyphosphate (polyP) is a ubiquitous and abundant compound found in bacteria, fungi, algae, plant, and animals. Among roles of intracellular polyP in bacteria are resistance and survival in the stationary phase of the growth against stress and stringent condition. Therefore, intracellular polyP is considered as a virulence factor of bacteria. In contrast, exogenous polyP has an antimicrobial activity against a variety of microorganisms. To date, much has been numerous studies of antibacterial effect of polyP against gram positive bacteria and fungi while relatively little reports have been published concerning gram negative bacteria. Here we describe bactericidal effect of polyP against gram negative periodontopathic bacterium, Porphyromonas gingivalis, and the transcriptional change by p

ORGANISM(S): Porphyromonas gingivalis

SUBMITTER: Ji-Hoi Moon 

PROVIDER: E-GEOD-11471 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress