IMR90 4hr bystander experiment 0.5Gy alpha particle strip dish format

ABSTRACT: Radiation affects tissue and cellular integrity at the level of DNA, protein and metabolites of the cell and extracellular space. The effects of radiation are not limited to targeted cells and tissue and radiation induced bystander effects are significant to exposed individuals in accidental or therapeutic situations. These non-targeted effects of radiation have been studied extensively at the low dose range where they appear to have adverse effects on cells and surrounding environments. The requirement of cellular contact and shared fluid media has been established as critical to the bystander effect yet there is not much known about the actual signaling mechanism and its ability to transmit the damaging effect over space and time. Experimental cell types and context within the tissue

ORGANISM(S): Homo sapiens

SUBMITTER: Shanaz Ghandhi 

PROVIDER: E-GEOD-12435 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress