Characterization of the autoaggregation response of Fusobacterium nucleatum

ABSTRACT: Fusobacterium nucleatum is a Gram negative oral bacterial species associated with periodontal disease progression. This species is perhaps best known for its ability to adhere to a vast array of other bacteria and eukaryotic cells. Numerous studies of F. nucleatum have examined various coaggregation partners and inhibitors, but it is largely unknown whether these interactions induce a particular genetic response. We tested coaggregation between F. nucleatum ATCC strain 25586 and various species of Streptococcus in the presence of a semi-defined growth medium containing saliva. We found that this condition could support efficient coaggregation, but surprisingly also stimulated a similar degree of autoaggregation. We further characterized the autoaggregation response, since few reports have

ORGANISM(S): Fusobacterium nucleatum

SUBMITTER: Justin Merritt 

PROVIDER: E-GEOD-18554 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress