Regional organization of gene expression in Streptomyces coelicolor

ABSTRACT: Based on the chromosomal locations of genes inferred from sequence analysis to be essential for the viability of Streptomyces coelicolor, Bentley et al. (Bentley et al., 2002) have suggested that a 4.9 Mb central region of the linear S. coelicolor chromosome encodes core functions expressed during vegetative growth of this species, while 1.5 Mb and 2.3 Mb chromosomal DNA segments lateral to this core encode auxiliary functions proposed to be required under other growth conditions. To examine this hypothesis and experimentally identify genes expressed during vegetative growth of S. coelicolor cultures, we used DNA microarrays to measure globally the abundance of S. coelicolor transcripts in cells growing in liquid medium. We found that, overall, genes corresponding to the 4.9 Mb core reg

ORGANISM(S): Streptomyces coelicolor

SUBMITTER: N Karoonuthaisiri 

PROVIDER: E-GEOD-2921 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress