Transcriptomic analyis of the response of porcine PBMC to stimulation with concanavalin A

ABSTRACT: One of the top priorities of the swine industry worldwide is to decrease the susceptibility of its animals to infectious diseases. There is therefore now an increased focus on the production of more M-bM-^@M-^\robustM-bM-^@M-^] animals, which have lower susceptibility to a broad range of infectious diseases. One general measure of immune competence is the proliferative response of peripheral blood mononuclear cells (PBMC) to mitogenic stimulation. Concanavalin A (ConA) is a mitogen that predominantly stimulates T lymphocytes within the PBMC fraction of blood. T cells play a crucial role in both cell-mediated and humoral immunity. Variation between individuals in the magnitude of the proliferative response to ConA has been estimated to have moderate heritability, and quantitative trait loci

ORGANISM(S): Sus scrofa

SUBMITTER: Jamie Wilkinson 

PROVIDER: E-GEOD-33760 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress