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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Global gene expression in adult cardiac fibroblasts transduced with cardiac transcription factor

ABSTRACT: Four transcription factors, GATA4, Hand2, MEF2C, Tbx5 (GHMT) activated cardiac gene expression in cardiac fibroblasts, suggesting that these factors are able to reprogram fibroblasts toward a cardaic cell fate. Total RNA isolated from adult cardiac fibroblasts transduced with empty retroviral vector or GHMT-retroviruses for 2, and 4 weeks.

ORGANISM(S): Mus musculus

SUBMITTER: Kunhua Song

PROVIDER: E-GEOD-37057 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Global gene expression in adult cardiac fibroblasts transduced with cardiac transcription factor

Project description:Four transcription factors, GATA4, Hand2, MEF2C, Tbx5 (GHMT) activated cardiac gene expression in cardiac fibroblasts, suggesting that these factors are able to reprogram fibroblasts toward a cardaic cell fate.

2012-04-06 | GSE37057 | GEO

Gene expression analysis of cardiac left-ventricle tissue from hybrid mice harboring the Scn5a-1798insD/+ mutation

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2012-12-01 | E-GEOD-27236 | biostudies-arrayexpress

Cardiac over-expression of Med13

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Transcription profile of zebrafish hand2 (hanS6 allele) mutant embryos at 19hpf

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Reprogramming of human fibroblasts toward a cardiac fate

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2013-01-18 | E-GEOD-43588 | biostudies-arrayexpress

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Genome-wide analysis of gene transcription in myocardium of mice transgenically expressing human cardiolipin synthase 1 (hCLS1) in cardiac tissue

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Dynamics of H3K4me2 during cardiac lineage reprogramming

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