Metabolism of four α-glycosidic linkage-containing oligosaccharides by Bifidobacterium breve UCC2003

ABSTRACT: Members of the genus Bifidobacterium are common inhabitants of the gastrointestinal tract of humans and other mammals, where they ferment many diet-derived carbohydrates that cannot be digested by their host. To extend our understanding of bifidobacterial carbohydrate utilisation, we investigated the molecular mechanisms by which various strains of Bifidobacterium breve metabolize four distinct α-glucose and/or α-galactose-containing oligosaccharides, namely raffinose, stachyose, melibiose and melezitose. Here we demonstrate that all B. breve strains examined possess the ability to utilise raffinose, stachyose and melibiose. However, the ability to metabolize melezitose was not ubiquitous for all tested B. breve strains. Transcriptomic and functional genomic approaches identified a gene cl

ORGANISM(S): Bifidobacterium breve

SUBMITTER: Mary O'Connell Motherway 

PROVIDER: E-GEOD-47448 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress