Transcription profiling of human omental adipose tissue in women with polycystic ovary syndrome (PCOS)

ABSTRACT: CONTEXT: The polycystic ovary syndrome (PCOS) is frequently associated with visceral obesity, suggesting that omental adipose tissue might play an important role in the pathogenesis of the syndrome. OBJECTIVE: The objective was to study the expression profiles of omental fat biopsy samples obtained from morbidly obese women with or without PCOS at the time of bariatric surgery. DESIGN: This was a case-control study. SETTINGS: We conducted the study in an academic hospital. PATIENTS: Eight PCOS patients and seven nonhyperandrogenic women submitted to bariatric surgery because of morbid obesity. INTERVENTIONS: Biopsy samples of omental fat were obtained during bariatric surgery. MAIN OUTCOME MEASURE: The main outcome measure was high-density oligonucleotide arrays. RESULTS: After statistical

ORGANISM(S): Homo sapiens

SUBMITTER: BELEN PERAL 

PROVIDER: E-GEOD-5090 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress