Regulatory landscape of a dimorphic and obligate intracellular pathogen

ABSTRACT: Both prokaryotic and eukaryotic organisms take deterministic decisions to reprogram cell fates. A macroscopic manifestation of such an event is the remodelling of the cells’ morphology and it typically is governed at the molecular scale by massive reorganization of the cellular transcriptome. With the regulation at the level of transcription initiation representing the most common form for such developmental reprogramming, cells typically rely on one or several master regulators to coordinate the the activity of hundreds of genes simultaneously by directly binding to their promoters. Despite the apparent simplicity of prokaryotes and their reduced genome size compared to that of their eukaryotic counterparts, free-living bacteria typically encode hundreds of transcription factors (TFs) i

ORGANISM(S): Waddlia chondrophila

SUBMITTER: Antonio Frandi 

PROVIDER: E-GEOD-68059 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress