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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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CUT&Tag chromatin profiling of H2AK119Ub, H3K27me3, H3K27ac and H3K4me3 histone in MC38 colon carcinoma cell line

ABSTRACT: The deubiquitinating enzyme BAP1 can remove the ubiquitination modification of H2AK119. To reveal the mechanism by which Bap1 deletion in MC38 colon carcinoma cell line causes an anti-tumor immune response from the epigenetic level, we generated CUT&Tag data of H2AK119Ub, H3K27me3, H3K27ac and H3K4me3 histone in MC38-Bap1-Wildtype and MC38-Bap1-Knockout isolated from Rag2-deficient mice.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Mingxia Li

PROVIDER: E-MTAB-10585 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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